Early Detection of Malnutrition in Oncology Patients and Elderly Patients

Официальное название

Early Detection of Malnutrition in Oncology Patients and People Over 65 Years of Age

Обзор

The project is a national, prospective, multicenter, non-interventional pilot project of malnutrition screening in the Czech Republic. The main goal of the project is to methodically prepare, implement and evaluate a pilot project that will verify the suitability of the proposed procedure for the early detection of malnutrition in oncology patients and hospitalised patients patients 65 years of age and older, as this has a significant effect on the quality of life and the effectiveness of the services provided oncological treatment.

Подробное описание

The main goal of the project is the early detection of malnutrition in oncology patients and hospitalised patients 65 years of age and older, as this has a significant effect on the quality of life and the effectiveness of the services provided oncological treatment.

Another goal of the project will be the creation of a unified diagnostic proposal process and methodological material for determining malnutrition. This process will then be designed as the standard of nursing practice for patients with an oncological diagnosis and for persons older than 65 years such that, so that an adequate nutritional intervention is started in time, which will lead to a higher tolerance of demanding treatment and thus to increase the quality of life.

The project will include testing the procedure on a sample of approx. 1,500 oncological and 500 geriatric patients.

The project is supported by the European Social Fund (Operational Program Employment plus) and the state budget of the Czech Republic and is registered by the Ministry of Labour and Social Affairs of the Czech Republic under ID: CZ.03.02.02/00/22\_005/0000282.

Вмешательства

• Диагностический тест Blood test
  Albumin, C-Reactive Protein, Cholesterol, Urea, Creatinine, Vitamin D
• Диагностический тест Bioelectrical Impedance Analysis
  Total Impedance, Segmental Muscle Analysis, Segmental Fat Analysis, Absolute Muscle Mass Value, Muscle Mass Index, Total Body Fat Percentage, Total Body Water, Phase Angle Measurement
• Другое Nutritional Risk Assessment Questionnaire
  Fill in the Questionnaire of the Working Group on Nutritional Care in Oncology and get nutrition risk score. The objective data includes weight loss in 6 months, current BMI and food tolerance, and oncological diagnosis including ongoing anti-cancer treatment.

Первичные конечные точки

• Number of people with malnutrition according to the PSNPO questionnaire [Срок оценки: Until 31. 3. 2026]

Вторичные конечные точки (1)

• Proportion of people with initiated nutritional intervention [Срок оценки: Until 31. 3. 2026]

Критерии участия

Критерии включения

Cohort Oncological patients:

• 18+
• an oncological diagnosis
• a survival prognosis of at least 3 months

Cohort Patients older than 65 years:

• 65+
• hospitalization at least 14 days or longer

Exclusion Criteria (both cohorts):

• not agreeing to participate in the project

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Чехия · 9 центров

• Brno University Hospital — Brno
• Masaryk Memorial Cancer Institute — Brno
• Hospital AGEL Nový Jičín a.s. — Nový Jičín
• University Hospital Olomouc — Olomouc
• University Hospital Pilsen — Pilsen
• Bulovka Hospital — Prague
• General University Hospital, Prague — Prague
• Military University Hospital, Prague — Prague
• … и ещё 1 центр

Идентификаторы

NCT: NCT06499623 · UZIS 2024/1

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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