Real-world Clinical Outcomes of Patients With Early-stage Lung Cancer After the Surgery
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Sublobar resection, Lobectomy.
- Кому может быть актуально
- Состояния в реестре: Lung Cancer. Базовые параметры: 18 лет — 85 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Real-world Clinical Outcomes of Patients With Early-stage Lung Cancer After the Surgery: A Retrospective Multi-center Study (EarlyLC-RW)
Обзор
The goal of this observational study is to evaluate the efficacy and long-term clinical outcomes of early-stage lung cancer patients who have received surgery using the real-world data. The main questions it aims to answer are: * What is the best surgical strategy for patients with early-stage lung cancer? * What are the risk factors for early-stage lung cancer? Participants will receive surgery and the study will analyze the real-world data.
Подробное описание
This observational study aims to comprehensively evaluate the effectiveness and long-term clinical outcomes of surgical interventions in early-stage lung cancer patients, utilizing real-world data.
Central to this investigation are two key questions:
* What is the optimal surgical approach for managing early-stage lung cancer? * What are the primary risk factors associated with the development of early-stage lung cancer? Participants will undergo surgical procedures, and through rigorous analysis of real-world data, this study endeavors to provide nuanced insights into these fundamental queries, fostering advancements in clinical decision-making and patient management strategies.
Вмешательства
- Другое Sublobar resection
Sublobar resection is a series of surgical approaches for lung cancer. - Другое Lobectomy
Lobectomy is the surgical approach for lung cancer.
Первичные конечные точки
- Disease-free survival(DFS) [Срок оценки: Defined as the time from the date of surgery until the date of first documented progression or death (by any cause in the absence of recurrence), whichever came first, assessed up to 10 years.]
Вторичные конечные точки (4)
- Overall Survival (OS) [Срок оценки: From date of diagnosis until the date of death from any cause, whichever came first, assessed up to 10 years.]
- 5-year Overall Survival (overall survival) Rate [Срок оценки: From date of surgery until date of death due to any cause. Assessed at 5 years.]
- Patterns of Relapse [Срок оценки: Within 10 years after surgery]
- Perioperative Complication rate [Срок оценки: Within 6 months after surgery]
Критерии участия
Критерии включения
- Aged between 18 and 85;
- Did not receive neoadjuvant therapy before surgery;
- No history of radiation therapy;
- Eastern Cooperative Oncology Group (ECOG) score is 0-1;
- Have complete clinically relevant information including imaging data;
- All patients underwent relevant preoperative examinations;
- Stage I lung cancer (International Association for the Study of Lung Cancer/The Union for International Cancer Control staging eighth edition);
Критерии исключения
- Have previously received chemotherapy, radiotherapy and other anti-tumor therapy;
- Data loss and error in medical records due to human/objective reasons.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- Shugeng Gao — Пекин
Идентификаторы
NCT: NCT06483698 · 23/516-4259