Clinical Characteristics and Analysis of Pituitary Complex and Rare Diseases
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Surgical Removal, Biopsy.
- Кому может быть актуально
- Состояния в реестре: Pituitary Diseases. Базовые параметры: Без ограничений · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
The goal of this observational study is to systematically describe the clinical characteristics and outcomes of patients with pituitary complex and rare diseases at Peking Union Medical College Hospital. The main questions it aims to answer are: * What are the influencing factors and rates of remission? * What are the comorbidities associated with these diseases? * What are the perioperative events, radiological findings, and pathological features? Researchers will compare different patient groups to see if there are significant differences in these outcomes. Participants will: * Undergo detailed clinical evaluations. * Provide medical history and data for analysis. * Participate in follow-up assessments to monitor disease progression and treatment outcomes.
Подробное описание
The study aims to provide a comprehensive analysis of pituitary complex and rare diseases at Peking Union Medical College Hospital. By leveraging a large cohort, the research will explore various clinical characteristics and outcomes. Specifically, the study will examine influencing factors and rates of remission, the presence of comorbidities, and perioperative events. Additionally, it will evaluate radiological findings and pathological features to better understand these conditions. Through this detailed investigation, the study seeks to enhance knowledge and inform clinical practice regarding the management and prognosis of pituitary complex and rare diseases.
Вмешательства
- Процедура Surgical Removal
Resection of pituitary pathologies. - Процедура Biopsy
Taking a small tissue or liquid sample from the pituitary pathologies and the affected area for examination and diagnosis
Первичные конечные точки
- Remission [Срок оценки: Postoperative one week and extends to the latest follow-up, estimated at up to 3 years]
Вторичные конечные точки (2)
- Disease Comorbidities [Срок оценки: From patient admission to an evaluation period extending up to the latest follow-up, estimately up to 3 years]
- Postoperative complications [Срок оценки: Postoperative one week and extends to the latest follow-up, estimated at up to 3 years]
Критерии участия
Критерии включения
- Diagnosed with rare sellar diseases including but not limited to pituitary adenomas (such as Thyrotropin-secreting pituitary adenomas, GH-secreting adenomas), craniopharyngiomas, Rathke's cleft cysts, sellar region germ cell tumors, cavernous sinus syndrome, and other diseases
- Detailed medical history, including clinical symptoms, treatment plans and follow-up outcomes
Критерии исключения
- Incomplete medical records, especially missing key imaging diagnostic results
- Patients with coexisting primary central nervous system diseases unrelated to sellar region diseases (such as severe traumatic brain injury)
- Patients whose sellar region pathological diagnosis was changed or overturned during the follow-up period
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- Peking Union Medical College Hospital — Пекин
Идентификаторы
NCT: NCT06435195 · K5112