Virtual Reality Cognitive Training for Older Adults With Mild Cognitive Impairment

Официальное название

Effects of Fully Immersive Virtual Reality Cognitive Training Based on Instrumental Activities of Daily Living for Older Adults With Mild Cognitive Impairment

Обзор

This study aims to (1) develop and assess the feasibility of a fi-VRCT program based on IADL for older adults with MCI, (2) implement and evaluate the effectiveness of the fi-VRCT program based on IADL in older adults with MCI, and (3) investigate the potential mechanism of the fi-VRCT program based on IADL for older adults with MCI and refine this intervention accordingly.

Подробное описание

As research on cognitive training methods for older adults with mild cognitive impairment (MCI) progresses, fully immersive virtual reality cognitive training (fi-VRCT) has emerged as a promising approach. While the benefits of fi-VRCT for enhancing cognitive function have been recognized, its potential to improve instrumental activities of daily living (IADL) and promote independence remains uncertain. This study addresses these questions by developing and validating a fi-VRCT program based on IADL to enhance cognitive and IADL performance among older adults with MCI.

Вмешательства

• Поведенческое fi-VR Cognitive Training
  All participants will 16 sessions over eight weeks, with two sessions per week, each lasting 70 minutes. Participants in the fi-VRCT will use the virtual reality system with head-mounted display and handheld controllers. The fi-VRCT will be administered by an experienced research assistant.
• Поведенческое Traditional Cognitive Training
  All participants will 16 sessions over eight weeks, with two sessions per week, each lasting 70 minutes. The CT control program will include cognitive board games designed to improve various cognitive capacities. Certified community occupational therapists will lead the CT control group.

Первичные конечные точки

• Changes scores of Montreal Cognitive Assessment (MoCA) [Срок оценки: At baseline, at week 9, and at 3-month follow-up.]
• Change scores of Wechsler Memory Scale (WMS) [Срок оценки: At baseline, at week 9, and at 3-month follow-up.]
• Change scores of Amsterdam Instrumental Activities of Daily Living Questionnaire, Short Version [Срок оценки: At baseline, at week 9, and at 3-month follow-up.]
• Change scores of Lawton Instrumental Activities of Daily Living [Срок оценки: At baseline, at week 9, and at 3-month follow-up.]

Вторичные конечные точки (2)

• Change scores of Digit Span [Срок оценки: At baseline, at week 9, and at 3-month follow-up.]
• Change scores of Stroop Color-Word Test [Срок оценки: At baseline, at week 9, and at 3-month follow-up.]

Критерии участия

Критерии включения

• Aged 65 or above.
• MoCA score between 18 and 25.
• Capability to follow directions and do tasks.

Критерии исключения

• History of dementia.
• Previous neurodegenerative illness diagnosis.
• Severe medical or surgical problems.
• Major psychological disorders.
• Inability to use VR system

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Лечение

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Публикации

• Chen IC, Wu CY, Hu YL, Huang YM. Development and Validation of Virtual Reality Cognitive Training for Older Adults with Mild Cognitive Impairment: Protocol for a Mixed-Methods Program Evaluation Study. Clin Interv Aging. 2024 Nov 9;19:1855-1865. doi: 10.2147/CIA.S471547. eCollection 2024. PMID 39539569

Идентификаторы

NCT: NCT06392412 · DaYehU

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗