Peer Support in Alcohol Dependence

Официальное название

Contribution of Addiction Peer Support on Adherence to Care and Clinical Outcomes in Alcohol Dependence: a Prospective Controlled Trial With Medico-economic Component

Обзор

Alcohol use disorder (AUD) affects between 4% and 6% of French adults, and requires appropriate medical treatment. However, 20-40% of patients with AUD are lost to follow-up at an early stage. Consequently, it is important for addiction departments to implement and evaluate innovative tools and interventions, including the involvement of peer support, to help patients remain in care, and to assess whether peer support has a positive impact on their clinical outcome. Addiction peer support specialists (APSSs) are individuals who have personally experienced addiction, and who have decided to use their experience to assist other people going through a similar situation, after completing a specific official graduation. Compared to other caregivers, APSSs may induce in patients a sense of identification which could improve the patient motivation to engage and remain in care. This is the main hypothesis and the main scientific objective of the PEERSIAD study, which will aim to confirm that accompanying patients with AUD using APSSs after alcohol detoxification, reduces the rate of lost-to-follow-up and improves the overall clinical outcome.

Вмешательства

• Поведенческое Quality life questionnaire AQoLS
  Quality life questionnaire AQoLS will be completed by patients of both arms at inclusion, three and six months after inclusion
• Поведенческое Quality life questionnaire Euroqol EQ-5D-5L
  Quality life questionnaire Euroqol EQ-5D-5L will be completed by patients of both arms at inclusion, three and six months after inclusion
• Другое Peer support consultations
  For patients included in the Peer support group, eight mandatory consultations with a peer support specialist will be performed between the inclusion visit and during the three following months. Patients can request additional consultations with the peer support specialist during the 6 first months of follow-up

Первичные конечные точки

• Unplanned cessation of care at 6 months [Срок оценки: At 6 months after inclusion]

Вторичные конечные точки (12)

• Number of unfulfilled consultations [Срок оценки: 6 months after inclusion]
• Euroqol-5D-5L questionnaire score [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• Difference in costs (in euros) [Срок оценки: At 1, 2 and 3 years after the beginning of implementation on French territory]
• Number of AUD criteria according to Diagnostic and Statistical Manual of Mental Disorders (DSM-5) [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• Alcohol Use Disorders Identification Test-Consumption (AUDIT-C) score [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• average number of standard drinks declared per week [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• Alcohol Quality of Life Scale (AQoLS) score [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• State-Trait Anxiety Inventory (STAI-Y) score [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• Montgomery-Åsberg Depression Rating Scale (MADRS) score [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• Cannabis Use Disorders Identification Test - Revised (CUDIT-R) score [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• type of opioid use [Срок оценки: At inclusion, 3 and 6 months after inclusion]
• frequency of opioid use [Срок оценки: At inclusion, 3 and 6 months after inclusion]

Критерии участия

Критерии включения

• Aged ≥ 18
• Socially insured
• Meeting DSM-5 criteria for alcohol use disorder (AUD)
• Abstinent from alcohol and involved in supervised alcohol withdrawal for at least 5 days and no more than 21 days (outpatient or inpatient)
• Starting a post-detoxification outpatient program

Критерии исключения

• Other severe substance use disorder, i.e. DSM-5 criteria ≥ 6 (excluding tobacco)
• Patient under protective measure (safeguard measure, guardianship) or deprived of liberty or in ordered care and hospitalization measures without consent.
• Inability to communicate and express oneself orally in French, compromising the possibility of exchanges between the Peer support and the patient.
• Psychiatric or cognitive comorbidities making inclusion impossible, at the investigator's discretion.
• Individual accompaniment by a Peer support in the 15 days prior to inclusion.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Нерандомизированное

Модель

Параллельные группы

Маскирование

Открытое

Основная цель

Организация здравоохранения

Центры проведения

Франция · 5 центров

• CH Le Vinatier — Bron
• Hôpital Beaujon — Clichy
• GH Nord, Hospices Civils de Lyon — Lyon
• CHS St Anne — Paris
• Bichat Hospital — Paris

Идентификаторы

NCT: NCT06381609 · 69HCL22_0901

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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