Effect of Anti-inflammatory Diet in Patients With Inflammatory Bowel Disease

Официальное название

Effects of Anti-inflammatory Diet on Inflammatory Markers, Anxiety, Depression and Quality of Life in Patients With Inflammatory Bowel Disease

Обзор

For the first time, this study developed an anti-inflammatory diet （AID） recipe suitable for Inflammatory bowel disease（IBD） patients and developed an AID application program to verify the intervention effect of AID on IBD patients, which not only promoted the application of AID in IBD patients and promoted the promotion of AID model, but also provided new ideas for the prevention and treatment strategies for IBD patients.

Подробное описание

This study aims to verify the intervention effect of AID on IBD patients, promote the promotion of AID model, and provide new ideas for the prevention and treatment strategies of IBD patients.

In this study, 66 IBD patients who met the inclusion criteria were divided into experimental group and control group by randomized controlled trial method. The experimental group was based on routine nursing measures, and the intervention group taught patients to take anti-inflammatory diet and use the anti-inflammatory diet mini-program developed by the researcher, daily anti-inflammatory diet, intervention time was 8 weeks, and observed the inflammatory indicators (white blood cells, neutrophils, erythrocyte precipitation, CRP), quality of life, anxiety and depression, self-efficacy and other conditions in the blood results of the patients before and after intervention.

Вмешательства

• Поведенческое Anti-inflammatory diet group
  Patients in the intervention group were given AID knowledge education, and patients were asked to pay attention to the "anti-inflammatory diet" wechat mini program developed by the researchers to teach patients how to use it, including the selection of anti-inflammatory diet, unsuitable anti-inflammatory diet, diet alarm clock, diet notes and other related functions. The missionary patients insisted on AID until reexamination 8 weeks later.

Первичные конечные точки

• C-reactive protein [Срок оценки: 8 weeks after intervention]
• Erythrocyte sedimentation rate (ESR) [Срок оценки: 8 weeks after intervention]
• Leukocyte [Срок оценки: 8 weeks after intervention]

Вторичные конечные точки (5)

• Self-Rating Anxiety Scale，SAS [Срок оценки: 8 weeks after intervention]
• Self-Rating depression scale，SDS [Срок оценки: 8 weeks after intervention]
• Simplified Chinese version of Inflammatory Bowel Disease Quality of Life Scale (IBDQ) [Срок оценки: 8 weeks after intervention]
• Inflammatory Bowel Disease Self-Efficacy Scale (IBD-SES) [Срок оценки: 8 weeks after intervention]
• Body Mass Index [Срок оценки: 8 weeks after intervention]

Критерии участия

Критерии включения

• Diagnosis of inflammatory bowel disease, the diagnostic criteria refer to the 2018 revised Consensus opinion on the diagnosis and treatment of inflammatory bowel disease;
• The patient has clear consciousness and certain understanding, language expression and writing ability;
• Patients participated in this study knowingly and voluntarily;
• At least 18 years old.

Критерии исключения

• cognitive impairment, mental illness, accompanied by mental disorders;
• Alcohol and drug abusers.
• The patient could not participate in the researcher due to the deterioration of the condition;
• Patients who voluntarily quit due to other reasons;
• Those who did not complete the assessment scale during the experiment.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Другое

Центры проведения

Китай · 1 центр

• The Fourth Affiliated Hospital of Zhejiang University School of Medicine — Yiwu

Идентификаторы

NCT: NCT06342011 · KY-2024-039

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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