Outcomes of Transanal Tran-section and Single-stapled (TTSS) Ileal Pouch-Anal Anastomosis

Ileal Pouch-Anal Anastomosis (IPAAI in Ulcerative Colitis (UC) patients is usually performed by double-stapling technique after rectal transection with a linear stapler. Double-stapling is increasingly criticized for the uneven longer cuffs and potential weak points. The Transanal Transection and Single-Stapled (TTSS) approach may potentially overcome the limitations of double-stapling. A single-stapled anastomosis may be accomplished through a transanal rectal transection followed by bottom-up dissection (transanal-ileal pouch-anal anastomosis) or through an abdominal, rectal dissection and subsequent transanal transection and single-stapled anastomosis. TTSS-IPAA approach was shown to provide reduced rectal cuff length and reduced rate of urgency at six months after stoma closure. However, the retrospective and single-center features of these findings may prevent a robust conclusion about the superiority of TTSS-IPAA. The purpose of this study is to compare short-term and functional outcomes of double-stapling versus TTSS techniques for IPAA in UC patients in a prospective multicentric cohort study.

• Pouch Function Score (PFS) [Срок оценки: 12 months after surgery or stoma closure]
• Pouch Function Score (PFS) [Срок оценки: 24 months after surgery or stoma closure]
• Postoperative complications [Срок оценки: 90 days after surgery]
• Anastomotic leak [Срок оценки: 90 days after surgery]
• Patients fit for stoma closure [Срок оценки: 12 months after surgery]
• Healthcare costs [Срок оценки: 12 months after surgery]
• Rectal cuff lenght [Срок оценки: At surgery]
• Pouch complications [Срок оценки: 24 months after surgery or stoma closure]