Prevalence of Dissociative Identity Disorder in At-risk Outpatient Groups Reporting Childhood Trauma.

Обзор

The investigators will study the prevalence of dissociative identity disorder (DID) in three populations at risk in cases of childhood psychotrauma : patients with a diagnosis of borderline personality, patients with a diagnosis of functional dissociative crises (FDC) and patients with early psychosis. The investigators will also study the prevalence of other dissociative disorders and the frequency of complex post-traumatic stress disorder. The investigators will also look for correlations between the type of maltreatment in childhood, the age of onset of trauma and the type of diagnosis of dissociative disorders. The investigators hope to include 150 borderline patients, 150 FDC patients and 50 early psychosis patients. Data collection will be done via a psychometric administration of 7 self-completion questionnaires as well as the completion of the SCID-D semi-structured interview.

Вмешательства

• Диагностический тест psychometric assessment
  Psychometric testing to assess trauma and dissociative disorders, and in particular dissociative identity disorder.
• Диагностический тест semi-structured clinical interview
  Semi-structured interview for the assessment of dissociative disorders (SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders)

Первичные конечные точки

• SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders / DSM = Diagnostic and Statistical Manual of Mental Disorders / ICD = International Classification of Diseases [Срок оценки: Inclusion visit]

Вторичные конечные точки (8)

• SCID-D : Semi-structured Clinical Interview for diagnosing DSM-5 and ICD-11 Dissociative Disorders [Срок оценки: Inclusion visit]
• CTQ-28 : Childhood Trauma Questionnaire [Срок оценки: Inclusion visit]
• life events inventory DSM-5 [Срок оценки: Inclusion visit]
• PCL-5 : Posttraumatic stress disorder CheckList-5 [Срок оценки: Inclusion visit]
• ITQ : International Trauma Questionnaire [Срок оценки: Inclusion visit]
• SDQ-20 : Somatoform Dissociative questionnaire [Срок оценки: Inclusion visit]
• DIS-Q : Dissociation Questionnaire [Срок оценки: Inclusion visit]
• DES : Dissociative Experience Scale [Срок оценки: Inclusion visit]

Критерии участия

I - Inclusion Criteria:

I-1: For all groups:

• Male or female
• Age > or = 18
• Enrolled in or benefiting from a social security scheme
• Patient fluent in French
• Patient willing to undergo a psychological evaluation between 1h30 and 3h30
• Patient with a known history of psychotrauma in childhood before the age of 18 (sexual abuse, mistreatment, school harassment, natural disasters, attacks, etc.).
• Patient having received and understood complete information on the organization of the research and having given written free and informed consent prior to participation in the study.

I-2 : Patients in the borderline group

• Patients with main diagnosis of emotionally labile personality
• Patients with at least one psychiatric hospitalization in the last 3 years

I-3 : Patients in the early psychosis group

Patient with a diagnosis of mental state at risk of psychosis according to the criteria defined by CAARMS (Comprehensive Assessment of At Risk Mental State) OR Patients diagnosed with a first psychotic episode on an outpatient basis or following a hospital stay

I-4 : Patients in the functional dissociative crises group

Patients diagnosed with functional dissociative crises by a specialized epileptologist

II- Non-inclusion criteria

• Impairment of the subject making it difficult or not impossible to participate in the trial or to understand the information provided to him/her
• Patients with specific difficulties in understanding SCID-D questions
• Psychiatric condition requiring hospitalization
• Patients with symptoms of recent toxic consumption (alcohol, cannabis, other ...) disrupting assessment responses
• Patient taking part in a pharmacological study involving a pro-dissociative molecule of the psychedelic type
• Pregnant, parturient or nursing mothers
• Person deprived of liberty by judicial or administrative decision
• Person in a life-threatening emergency
• An adult under legal protection (guardianship, curatorship, safeguard of justice)
• Person unable to give consent and not subject to a legal protection measure

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Нерандомизированное

Модель

Параллельные группы

Маскирование

Открытое

Основная цель

Диагностика

Центры проведения

Франция · 3 центра

• Centre Psychothérapique de Nancy - CLIP — Nancy
• Centre Psychothérapique de Nancy - CMP Jacquard et Des Près — Nancy
• CHRU Nancy - Neurology department — Nancy

Идентификаторы

NCT: NCT06330467 · 2023-A02442-43 · RIPH 2023-02

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗