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Идёт набор NCT06314204

Impact of Cannabis Consumption on the Course, Modalities of Hospitalization and the Short-term Prognosis of Inpatients Suffering From Psychotic Symptoms

— Наблюдательное Psychotic; Disorder, Cannabis

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
Это наблюдательное исследование: исследуемое лечение участникам по протоколу не назначают.
Кому может быть актуально
Состояния в реестре: Psychotic; Disorder, Cannabis. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Франция
Следующий шаг
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Официальное название

Impact of Cannabis Consumption on the Course, Modalities of Hospitalization and the Short-term Prognosis of Inpatients Suffering From Psychotic Symptoms : Multicenter Comparative Observational Study

Обзор

Few studies have evaluated, in patients with symptomatology the impact of cannabis use on the duration of hospitalization and on short- and medium-term developments. The objective of this study will be to assess the impact of cannabis on the duration, the hospitalization and the short- and medium-term evolution of patients with psychotic symptoms and cannabis use. We hypothesize that these patients (in comparison with patients with psychotic symptomatology and not using cannabis) would be hospitalized more long, exposed to a higher risk of resistance to the usual therapeutics, would have a lack of therapeutic alliance and insight, relapses and hospitalizations more frequent, more marked negative symptoms and lower quality remission. They would also be more prone to impulsive and aggressive behaviour.

Подробное описание

Several studies have reported that cannabis use worsen the prognosis of psychiatric pathologies in general and psychotic in particular.

Few or no studies have evaluated the impact of cannabis consumption on patients with psychotic symptoms during their hospitalization (duration, type of hospitalization, quality of relationship with staff hospital), and on the short-term prognosis.

The objective of this study will be to assess the impact of cannabis on the duration of the hospitalization and the short- and medium-term evolution of patients with a psychotic symptomatology and cannabis use. Making the hypothesis that these patients (compared to patients with symptomatology psychotic and not using cannabis) would be hospitalized longer, exposed at a higher risk of resistance to the usual therapies, to have a lack of alliance therapeutic and insight, relapses and more frequent hospitalizations and symptoms.

They would also be more likely to have lower quality. They would also be more likely to be impulsive, and have aggressive behaviours.

Первичные конечные точки

  • PANSS: Positive and Negative Syndrom Scale [Срок оценки: AT the beginning of the study, before any procedure, (T1)]
  • PANSS: Positive and Negative Syndrom Scale [Срок оценки: Approximatively 2 or 3 weeks after T1,On the day of the discharge (T2)]
  • PANSS: Positive and Negative Syndrom Scale [Срок оценки: 1 month after the discharge (T3)]
  • PANSS: Positive and Negative Syndrom Scale [Срок оценки: 3 month after the discharge (T4)]
  • MCQ-SF :Marijuana Craving Questionnaire- Short Form [Срок оценки: AT the beginning of the study, before any procedure (T1)]
  • MCQ-SF :Marijuana Craving Questionnaire- Short Form) [Срок оценки: Approximatively 2 or 3 weeks after T1 ,On the day of the discharge (T2)]
  • MCQ-SF :Marijuana Craving Questionnaire- Short Form) [Срок оценки: one month after the discharge]
  • MCQ-SF :Marijuana Craving Questionnaire- Short Form) [Срок оценки: three month after the discharge]
  • CGI: Clinical Global Impression [Срок оценки: AT the beginning of the study, before any procedure (T1)]
  • CGI: Clinical Global Impression [Срок оценки: Approximatively 2 or 3 weeks after T1 ,On the day of the discharge (T2)]

Критерии участия

Критерии включения

  • Hospitalized in psychiatry regardless of the mode of hospitalization
  • With or without protective measures (guardianship or curatorship)
  • Presenting psychotic symptoms (schizophrenia, schizo affective disorder, thymic disorder with psychotic characteristic, psychotic disorder substance-induced, brief psychotic disorder, schizophrenic disorders, delirious disorders)
  • Members of the social security system
  • Enlightened information

Критерии исключения

  • Degenerative neurological pathologies or mental retardation
  • Psychotic disorders secondary to generalized medical conditions(epilepsy, delirium tremens, tumors, etc.)
  • Other psychiatric pathologies

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения
Другое

Центры проведения

Франция · 1 центр
  • unité de recherche clinique de l'E.P.S de Ville Evrard — Neuilly-sur-Marne

Идентификаторы

NCT: NCT06314204 · 2015-A01222-47

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗