Exercise Rehabilitation for Children With Asthma

Официальное название

Personalized Exercise Rehabilitation for Pediatric and Adolescent Asthma: A Comprehensive Intervention Study

Обзор

Asthma, a prevalent chronic condition among children and adolescents, substantially impairs their quality of life. In addressing this significant health concern, this study focuses on the potential of a customized exercise rehabilitation program tailored for this young demographic. By employing a randomized controlled trial design, the research aims to divide participants into two distinct groups: one undergoing a personalized exercise regimen and the other receiving standard medical care. The 12-week intervention for the exercise group includes a combination of aerobic activities, strength training, and targeted breathing exercises. The study's primary aim is to rigorously evaluate the impact of this specialized exercise protocol on critical health aspects such as lung function, physical endurance, frequency of asthma attacks, and overall quality of life. The anticipated findings from this research are expected to shed new light on effective asthma management strategies and offer invaluable guidance for clinical practices dedicated to improving health outcomes in young asthma patients.

Вмешательства

• Поведенческое Personalized Exercise Rehabilitation
  The experimental group will participate in a 12-week exercise intervention program, carefully transitioning from moderate-intensity interval training to high-intensity interval training. The progression of exercise intensity will be regularly adjusted based on each child's tolerance, ensuring a personalized approach to the regimen. The exercise program is structured into three phases: an adaptation phase, an intensification phase, and a consolidation phase. For each participant, the intensity of

Первичные конечные точки

• Lung Function [Срок оценки: up to 24 weeks]
• Daily Physical Activity Level [Срок оценки: up to 24 weeks]

Вторичные конечные точки (7)

• Asthma Control Status [Срок оценки: up to 24 weeks]
• Fractional Exhaled Nitric Oxide (FeNO) [Срок оценки: up to 12 weeks]
• Body Composition [Срок оценки: up to 24 weeks]
• Sleep [Срок оценки: up to 24 weeks]
• Health Related Quality of Life [Срок оценки: up to 24 weeks]
• Anxiety and Depression [Срок оценки: up to 24 weeks]
• Inflammatory Mediators [Срок оценки: up to 12 weeks]

Критерии участия

Критерии включения

• Diagnosed with bronchial asthma;
• No acute asthma attacks in the past three months;
• Currently undergoing stable prophylactic treatment for asthma, with no changes in the treatment plan in the past three months.

Критерии исключения

• Suffering from other severe heart, lung, or musculoskeletal diseases;
• Frequent acute asthma attacks or recent hospitalization records;
• Changes in asthma medication treatment plan in the last three months;
• Currently participating in other clinical trials that could affect the results of this study;
• Any medical contraindications, such as severe exercise-induced asthma or other health issues affecting the ability to exercise;
• Severe psychological or behavioral issues that may affect participation in training or adherence to the research protocol.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Поддерживающая терапия

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT06272604 · 2024-IRB-0015-P-01

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

Открыть это исследование на ClinicalTrials.gov ↗