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Набор скоро начнётся NCT06247059

Reducing Respiratory Virus Transmission in Bangladeshi Classrooms

Без фазы С лечением SARS-CoV2 Infection Influenza Viral Infections Respiratory Viral Infection

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Box Fan, UV Germicidal Irradiation Lamp Unit, Combined: Box Fan and UV Germicidal Irradiation Lamp Units.
Кому может быть актуально
Состояния в реестре: SARS-CoV2 Infection, Influenza Viral Infections, Respiratory Viral Infection. Базовые параметры: 9 лет — 12 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Список центров уточняется — проверьте первичный протокол.
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

This study will test if affordable air cleaning devices (box fans with a filter attached and/or ultraviolet light lamps) installed in classrooms can reduce the number of viral respiratory illnesses schoolchildren experience.

Подробное описание

This cluster-randomized controlled trial in Bangladesh schools will examine whether low-cost air filtration and/or human-safe ultraviolet germicidal light interventions can reduce the incidence of schoolchildren's respiratory viral infections. The main study objectives are:

1. Pilot and optimize an intervention to filter classroom air. 2. Pilot and optimize an intervention to treat classroom air with ultraviolet light. 3. Assess the separate and combined effect of air filtration and ultraviolet light on the incidence of polymerase chain reaction (PCR) confirmed illness from respiratory viruses.

Methods: The study will take place in 60 government primary schools in Dhaka, Bangladesh. Within each enrolled school, 5 classrooms of students in grades 3, 4 and 5 will be randomly assigned to receive:

1. Box fans with a filter attachment. 2. 220 nanometer (nm) wavelength ultraviolet light air cleaner lamps. 3. Both the box fans with a filter and the 220 nm ultraviolet lamps. 4. No device: a control group that receives no additional device ("standard of care"). Two classrooms within each school will be assigned as controls.

Why does this matter?: Clarifying the impact of low-cost practical solutions could support the adoption of these strategies that could reduce influenza and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission in schools in order to reduce the burden of respiratory illness in these communities.

Вмешательства

  • Устройство Box Fan
    Classrooms assigned to this arm will be equipped with 2 - 8 box fans each with a single minimum efficiency reporting value-14 (MERV-14) filter sufficient to increase effective air changes per hour to 12 based on the clean air delivery rate measured in cubic feet per minute of the box fan + filter \* 60 divided by the room volume.
  • Устройство UV Germicidal Irradiation Lamp Unit
    Classrooms assigned to this arm will be equipped with one or two 222nm wavelength light ultraviolet germicidal irradiation lamp units (number of units per classroom based on room volume).
  • Устройство Combined: Box Fan and UV Germicidal Irradiation Lamp Units
    Classrooms assigned to this arm will be equipped with both box fans and UV germicidal irradiation lamp units.

Первичные конечные точки

  • Total number of symptomatic respiratory illness episodes due to either Influenza or SARS- CoV-2 [Срок оценки: Over 40 weeks of observation]
Вторичные конечные точки (4)
  • Total number of symptomatic influenza-like illness episodes [Срок оценки: Over 40 weeks of observation]
  • Total number of symptomatic influenza episodes [Срок оценки: Over 40 weeks of observation]
  • Total number of symptomatic SARS-CoV2 episodes [Срок оценки: Over 40 weeks of observation]
  • Total number of student absentee episodes [Срок оценки: Over 40 weeks of observation]

Критерии участия

Критерии включения

  • Schoolchildren of Bangladesh Government-run primary schools in Dhaka, Bangladesh ages 9 - 12 years, of all gender identifiers (male, female, transgender, prefer not to designate), without specific ethnic selection amongst standard school children of Bangladesh government schools in Dhaka, Bangladesh.

Критерии исключения

  • School children of non-Bangladesh Government-run primary schools and/or schoolchildren who do not attend a Bangladesh Government-run primary school in Dhaka, Bangladesh.
  • School children who are not able to or have a contraindication with the ability to comply with study procedures.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Рандомизированное
Модель
Параллельные группы
Маскирование
Простое слепое
Основная цель
Профилактика

Центры проведения

Список центров уточняется — проверьте первичный протокол.

Идентификаторы

NCT: NCT06247059 · 73657

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗