Peking University Birth Cohort in Weifang (PKUBC-WF)
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: No Interventions.
- Кому может быть актуально
- Состояния в реестре: Health Problems in Pregnancy, Pregnancy Outcomes, Gestational Diabetes, Gestational Hypertension. Базовые параметры: от 18 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Peking University Birth Cohort in Weifang
Обзор
The PKUBC-WF is a prospective cohort study carried out in Weifang city of Shandong, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and child health. Data are collected regarding environmental, nutritional and lifestyle exposures as well as short-term and long-term health outcomes of mothers and their children from birth to before 18 years old. Biological samples including peripheral blood, urine, placenta, umbilical cord, cord blood, and faeces are also collected.
Подробное описание
Maternal and child health is of great concern globally. Early life phase of a fetus and infant is a critical period for the development of health and disease in the whole life. Exposure of negative environmental, nutritional and lifestyle factors in pregnant women during this period can have adverse effects on fetal and infant. In addition, for mothers, complications during pregnancy could also have a negative effect on long-term health of mothers, such as diabetes, hypertension. Thus, the Peking University Birth Cohort in Weifang is primarily aimed to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and child health. Data are collected regarding environmental, nutritional and lifestyle exposures as well as short-term and long-term health outcomes of mothers, husbands and their children from birth to before 18 years old. Biological samples including peripheral blood, urine, placenta, umbilical cord, cord blood, and faeces samples are also collected.
Вмешательства
- Другое No Interventions
No intervention This is an observational study without any intervention
Первичные конечные точки
- Numbers and morbidity of participants with pregnancy complications [Срок оценки: At delivery]
- Numbers and morbidity of participants with adverse pregnancy outcomes [Срок оценки: At delivery]
Вторичные конечные точки (10)
- Weight in kilogram changes during childhood [Срок оценки: At birth and age at 6 weeks, 6 months, 12 months, 2 years, 3 years, 6 years, 9 years, 12 years, 15 years, and 17 years]
- Height in centimeter changes during childhood [Срок оценки: At birth and age at 6 weeks, 6 months, 12 months, 2 years, 3 years, 6 years, 9 years, 12 years, 15 years, and 17 years]
- Early Child development [Срок оценки: Age at 6 weeks, 6 months and 12 months]
- Incidence of diabetes mellitus in women [Срок оценки: 6 weeks after delivery and 3 years after delivery]
- Incidence of hypertension in women [Срок оценки: 6 weeks after delivery and 3 years after delivery]
- Incidence of child overweight and obesity [Срок оценки: At birth and age at 6 weeks, 6 months, 12 months, 2 years, 3 years, 6 years, 9 years, 12 years, 15 years, and 17 years]
- Incidence of autism spectrum disorder in children [Срок оценки: Age at 2 years, 3 years]
- Incidence of attention-deficit/hyperactivity disorder in children [Срок оценки: Age at 6 years]
- Incidence of anxiety in adolescents [Срок оценки: Age at 9 years, 12 years, 15 years, and 17 years]
- Incidence of depression in adolescents [Срок оценки: Age at 9 years, 12 years, 15 years, and 17 years]
Критерии участия
Критерии включения
- Pregnant woman
- Pregnant women, 6-13\^+6 gestational weeks
- Resided in Weifang in the past half years and have no plan to move out after delivery
- Pregnant women who plan to have antenatal care and delivery in Weifang maternal\&Child Hospital.
- Pregnant women who is willing to participate in this study with informed consent
- Pregnant woman's husband
- His wife was eligible for enrollment
- He is the biological father of the child (his wife's current pregnancy)
- Pregnant women's husband who is willing to participate in this study with informed consent
- Offspring 4. Children born to pregnant women who met the inclusion criteria after enrolling in this study.
5\. Before the age of 8 years, his/her mother provided written informed consent. 6. After 8 years old, he/she agreed to continue this study and signed the informed consent.
Критерии исключения
- Participants who cannot communicate normally.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- Peking University — Пекин
Идентификаторы
NCT: NCT06234332 · PKUBC-WF