Идёт набор NCT06115148

Breath Analysis & Malnutrition

Без фазы С лечением Malnutrition

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: Feeding, Fasting.
Кому может быть актуально: Состояния в реестре: Malnutrition. Базовые параметры: 18 лет — 95 лет · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: США
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Breath Ammonia as a Malnutrition Screening Tool

Обзор

The purpose of this research study is to understand how breath is related to nutritional status. The procedures involved in this study include blood and breath sampling, questionnaires about health history, medications, nutritional status and diet, and a physical examination. Breath markers will be compared between individuals with and without malnutrition and be compared to indicators of malnutrition. Some individuals will undergo an interventional study involving 2 days of consuming study beverages and fasting along with providing additional breath samples to see if the breath changes in response to short-term changes in nutritional status.

Подробное описание

Research Summary: This research involves a cross-sectional study investigating whether breath molecules (in particular ammonia and nitric oxide) are related to the presence and magnitude of malnutrition as measured by the gold-standard nutrition focused physical examination (NFPE). It also involves an interventional study in a subset of cross-sectional participants looking at whether acute changes in nutritional status through anabolic feeding protocols or fasting protocols is related to short term changes in breath molecules.

Purpose of the Research: The purpose is to identify early evidence of breath biomarkers of malnutrition. It uses a combination of breath analysis and current malnutrition screening tools (questionnaires).

Вмешательства

Другое Feeding
Nutrition beverages will be provided to meet the nutrient needs described in the Feeding Arm.
Другое Fasting
Water will be consumed as described during the Fasting Arm.

Первичные конечные точки

Breath Ammonia [Срок оценки: Interventional: Upon waking and after the intervention, but before bed on each of the 1-day intervention arms]

Вторичные конечные точки (2)

Breath volatile organic compounds [Срок оценки: Interventional: Upon waking and after the intervention, but before bed on each of the 1-day intervention arms]
Fractional Exhaled Nitric Oxide [Срок оценки: Interventional: Upon waking and after the intervention, but before bed on each of the 1-day intervention arms]

Критерии участия

Критерии включения

Age: 18-95 years
Malnutrition group (Cross-sectional study only); not involved in intervention: Diagnosed with malnutrition (verified in medical history)