Assessing the Use of MY-RIDE, a Just-in-time Adaptive Intervention, to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness

Обзор

The purpose of this study is to determine whether Motivating Youth to Reduce Infections, Disconnections, and Emotion dysregulation (MY-RIDE) decreases substance use , to determine whether MY-RIDE increases human immunodeficiency virus (HIV) prevention strategies and to evaluate MY-RIDE effects on willingness to take Pre-Exposure Prophylaxis (PrEP), stress, substance use urge, and use of mental health and substance use services when compared to attention control youth

Вмешательства

• Поведенческое Attention-control group
  Participants will receive a one-hour general health promotion session from a nurse and be issued a phone that will deploy the EMA on the same schedule as the intervention arm. They will also receive usual care from the clinics, drop-in center, and shelter recruitment sites. Usual care includes accessing social workers and case managers for immediate housing, food, and clothing needs and assistance in navigating the local Continuum of Care system to access social services.
• Поведенческое MY-RIDE group
  MY-RIDE has three main components: 1) One nurse-led face-to-face session; 2) three months of Ecological Momentary Assessments (EMA) with personalized messaging delivered by phone in real-time in response to one's current risk; and 3) access to on-demand healthcare/PrEP navigation and referrals.

Первичные конечные точки

• Change in substance use [Срок оценки: baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention]

Вторичные конечные точки (3)

• Change in condom use [Срок оценки: baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention]
• Change in PrEP uptake as assessed by the self reported tool [Срок оценки: baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention]
• Change in sexually transmitted infections (STIs) [Срок оценки: baseline, end of intervention (3 months after baseline), 3 months after intervention, 6 months after intervention, and 12 months after intervention]

Критерии участия

Критерии включения

• have engaged in substance use (alcohol or illicit drugs)
• speak English
• are experiencing homelessness
• engaged in sexual activity in the last 6 months or plan to in the next month
• are not planning to move out of the metro area during the 15-month study period.

Критерии исключения

• Youth Experiencing Homelessness (YEH) who have low literacy based on the Rapid Estimate of Adult Literacy in Medicine-Short Form (scores < 4)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Профилактика

Центры проведения

США · 1 центр

• The University of Texas Health Science Center at Houston — Houston

Публикации

• Santa Maria D, Padhye N, Businelle M, Slesnick N, Ricondo S, Lightfoot M. Just-in-Time Adaptive Intervention to Improve HIV Prevention and Substance Use in Youth Experiencing Homelessness (MY-RIDE): Protocol for a Randomized Controlled Trial. JMIR Res Protoc. 2025 Oct 10;14:e78006. doi: 10.2196/78006. PMID 41072013

Идентификаторы

NCT: NCT06074354 · HSC-SN-23-0360 · 1R01NR020997-01A1

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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