Eccentric Resistance Training Among Individuals With Chronic Heart Failure

Официальное название

Effects of Eccentric Resistance Training on Ventricle Functions and Aerobic Capacity Among Individuals With Chronic Heart Failure

Обзор

To determine the effects of eccentric resistive training on ventricle functions and aerobic capacity as compared to a resistance and aerobic training among Heart failure (HF)

Вмешательства

• Другое Eccentric Resistive Training + Aerobic training Group
  Eccentric Resistive training includes upper limb (biceps and triceps) and lower limb large muscle training (quadriceps and hamstrings) 2 sets of 12 repetitions (reps) for each group of muscles in lengthened position for eccentric training in approx. 20 minutes (min). Intensity will be based on 1 repetition maximum (1RM) starting from 20% of (1RM) and its intensity in percentage will be progress by 10% after every two weeks. Stair descending training and squatting position and eccentric hamstring
• Другое Resistance Training + Aerobic training Group
  Resistive training (concentric) includes Upper limb (biceps and triceps) and lower limb large muscle training (quadriceps and hamstrings), 2 sets of 12 reps for each group of muscles in approx. 30 min. Intensity will be based on 1 repetition maximum (1RM) starting from 20% of (1RM) and its intensity in percentage will be progress by 10% after every two weeks. Stair climbing training and quadriceps training + standing hamstring curls with weight at ankle for lower limb concentric training progres
• Другое Aerobic training Group
  Aerobic training as a control will be given to this group as well for approximately 60 minutes per session. Aerobic training exercise will be completed via a ergometer/stationary cycle; type will be continuous aerobic exercise and intensity of 60% of max HR (or peak VO2) in HF individuals.

Первичные конечные точки

• Ventricle Functions [Срок оценки: 12 week]
• Aerobic Capacity [Срок оценки: 12 week]

Вторичные конечные точки (9)

• Quality of life (Minnesota Living with Heart Failure Questionnaire) [Срок оценки: 12 week]
• Strength [Срок оценки: 12 week]
• Maximal strength of respiratory muscles [Срок оценки: 12 week]
• Forced Expiratory Volume in 1 second (FEV1) [Срок оценки: 12 week]
• Forced vital Capacity (FVC) [Срок оценки: 12 week]
• Peak Expiratory Flow (PEF) [Срок оценки: 12 week]
• Cardiac Risk Factors - Blood Pressure [Срок оценки: 12 week]
• Cardiac Risk Factors - Body mass index [Срок оценки: 12 week]
• Cardiac Risk Factors - Lipid profile [Срок оценки: 12 week]

Критерии участия

Критерии включения

• Diagnosis of Chronic HF and currently stable with optimal medical therapy
• Chronic Heart failure with ejection fraction > 30 %
• Patient able to safely perform lower limb exercise will be check by six- minute walk test (6 MWT)

Критерии исключения

• Those Heart failure patient whose are in acute phase or planed for any immediate medical intervention
• Already participating in cardiac rehabilitation
• New York Heart Association (NYHA) Classification of HF class IV HF symptoms
• Co-existent other disease such as asthma/ COPD/interstitial lung disease.
• Symptomatic Second degree or third degree heart block.
• ECG with uncontrolled ventricular arrhythmia
• Limited Exercise ability due to neurologic or orthopedic impairments of the legs (will cross-check with 6 MWT)

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Двойное слепое

Основная цель

Другое

Центры проведения

Пакистан · 2 центра

• Pakistan Railway Hospital — Rawalpindi
• Rawalpindi Institute of Cardiology — Rawalpindi

Идентификаторы

NCT: NCT06032780 · ISB/REC/PhD/01199 Iqbal Tariq

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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