Adaptation of Individual Dialectical Behavior Therapy Intervention for Transdiagnostic Treatment of Emotional Disorders

Anxiety and depressive disorders, referred to as emotional disorders, have high rates of prevalence, recurrence, and functional impairment. Transdiagnostic psychotherapy targeting shared features of these disorders has recently emerged. Dialectical behavior therapy (DBT) for the transdiagnostic treatment of emotional disorders is a promising approach, as results of preliminary studies for use in a broad range of mental disorders are encouraging. Since there is a lack of research on transdiagnostic psychotherapy in Taiwan, the investigators thus propose this 3-year randomized controlled trial to test the efficacy of a modified DBT for the treatment of transdiagnostic emotional disorders and to further evaluate whether the efficacy of modified DBT differs in the specific emotional disorders. This 3-year intervention trial has a randomized, controlled, two-center, and single-blinded design with two parallel groups. The trial will be conducted in the psychiatry departments of two medical centers, employing identical protocols. Participants will be recruited and randomly allocated 1:1 to one of two study arms. The modified DBT protocol in an individual therapy format consists of 15 weekly individual sessions, each lasting 50 minutes. A minimum of 250 participants will be included based on sample size estimation. Assessments will take place before the start of the trial, at the end of the trial, and at a 3-month follow-up. Primary outcomes will be the severity of depression and anxiety, rated by blind assessors. Secondary outcomes include disorder-specific symptoms, disorder severity, functional impairment, quality of life, and emotion regulation biases. The investigators will also examine the treatment mechanisms and treatment processes.

• Change of total score of Depression, Anxiety, and Stress Scales (DASS-21) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Patient Health Questionnaire-9 items (PHQ-9) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Generalized Anxiety Disorder-7 items (GAD-7) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Panic Disorder Severity Scale- Self Rating (PDSS-SR) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Penn State Worry Questionnaire (PSWQ) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Short Form Social Interaction Anxiety (SIAS) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Short Form Social Phobia Scale (SPS) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Difficulties in Emotional Regulation Scale (DERS) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of International Positive and Negative Affect Schedule-Short Form (PANAS-SF) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form (Q-LES-Q SF) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of The Work and Social Adjustment Scale (WSAS) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]
• Change of total score of skills subscale (DSS) of the DBT Ways of Coping Checklist (DBT-WCCL) [Срок оценки: Pretreatment (0 weeks), Posttreatment (20 weeks), 12-week follow-up (32 weeks)]