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Идёт набор NCT05961748

Registry of Multicenter Brain-Heart Comorbidity in China

— Наблюдательное Ischemic Heart Disease Cardiac Arrest Atrial Fibrillation Heart Failure

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Multi-disciplinary assessment.
Кому может быть актуально
Состояния в реестре: Ischemic Heart Disease, Cardiac Arrest, Atrial Fibrillation, Heart Failure. Базовые параметры: от 18 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
Китай
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

This study is a multi-center, prospective, registry study. This research was supported by the National Key Research and Development Program. To establish a domestic multi-center, large-scale "brain-heart comorbidity" dynamic database platform including clinical, sample database, image and other multi-dimensional information requirements, through the construction of a multi-center intelligent scientific research integration platform based on artificial intelligence. Any of newly diagnosed cardiovascular related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) \[i.e., ACS\], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels). The data is stored on the brain-heart comorbidity warehouse via a physical server at the institution's data centre or a virtual hosted appliance. The brain-heart comorbidity platform comprises of a series of these appliances connected into a multicenter network. This network can broadcast queries to each appliance. Results are subsequently collected and aggregated. Once the data is sent to the network, it is mapped to a standard and controlled set of clinical terminologies and undergoes a data quality assessment including 'data cleaning' that rejects records which do not meet the brain-heart comorbidity quality standards. The brain-heart comorbidity warehouse performs internal and extensive data quality assessment with every refresh based on conformance, completeness, and plausibility (http://10.100.101.65:30080/login).

Вмешательства

  • Другое Multi-disciplinary assessment
    Multi-disciplinary assessment

Первичные конечные точки

  • Rate of Participants with Composite of All-Cause Mortality and Cardiovascular Outcomes [Срок оценки: At discharge/30 days]
  • All-Cause Mortality [Срок оценки: At discharge/30 days]
  • Rate of Participants with Composite of Cardiovascular Outcomes [Срок оценки: At discharge/30 days]

Критерии участия

Критерии включения

  • age > 18 years old
  • Any of newly diagnosed cardiovascular-related diseases were identified via ICD-10-CM codes: I21, I22, I24 (Ischaemic heart diseases) \[i.e., ACS\], I46 (cardiac arrest), I48 (Atrial fibrillation/flutter), I50 (Heart failure), I71 (Aortic disease), I60 (subarachnoid hemorrhage), I61 (intracerebral hemorrhage), I63 (Cerebral infarction), I65 (Occlusion and stenosis of precerebral arteries), I66 (Occlusion and stenosis of cerebral arteries), I67.1 (cerebral aneurysm), I67.5 (moyamoya diseases), Q28.2 (Arteriovenous malformation of cerebral vessels).

Критерии исключения

·refuse to participate in the registry

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

Китай · 14 центров
  • Beijing Tiantan Hospital, Capital Medical University — Пекин
  • Beijing Anzhen Hospital, Capital Medical University — Пекин
  • Beijing Chaoyang Hospital, Capital Medical University — Пекин
  • Chinese People's Liberation Army (PLA) General Hospital — Пекин
  • Peking University First Hospital — Пекин
  • Xuanwu Hospital, Capital Medical University — Пекин
  • The First Affiliated Hospital of Fujian Medical University — Фучжоу
  • The First Affiliated Hospital of Xiamen University — Xiamen
  • … и ещё 6 центров

Публикации

  • Lu J, Lin F, Weng J, Lyu J, Zhang L, Song W, Zhu B, Ma M, Xu H, Xue J, Liu M, Zhang Y, Chen Y, Li R, Wang K, Liu H, Chen X, Zhao J, Liu MJ. Serum Lipid Profiles and the Burden of Polyvascular Atherosclerosis: A Cross-Sectional CTA-Based Study in a Chinese Cohort. J Stroke Cerebrovasc Dis. 2026 Jul 30:108715. doi: 10.1016/j.jstrokecerebrovasdis.2026.108715. Online ahead of print. PMID 42532457

Идентификаторы

NCT: NCT05961748 · KY2022-221-02

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗