Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia

Официальное название

Impact of the Choice of Gastric Tube Placement Sites on the Incidence of Ventilator Associated Pneumonia and Other Complications in the Intensive Care Unit

Обзор

In intensive care, many gastric tubes are inserted on a regular basis. There are different practices in terms of the location of the gastric tube. In some cases, the tube is inserted through the nose and in others, it is inserted through the mouth. In the literature and in practice, these gastric tubes create discomfort and complications that have an impact not only on the patient, but also on the treatments and the length of the patient's stay in hospital. Nosocomial Ventilator Associated Pneumonia is the most serious common complication for patients intubated with a gastric tube. It is possible that placement site may have an impact on the risk of developing Ventilator Associated Pneumonia, particularly by increasing the risk of bacterial pullulation opposite the sinuses when the tube is placed via the nasal route. Investigator hypothesises that placing the gastric tube orally will reduce the rate of ventilator-associated pneumonia compared with the nasal route in mechanically ventilated intensive care patients.

Вмешательства

• Другое nasogastric tube and orogastric tube
  nasogastric tube in period 1 and orogastric tube in period 2
• Другое orogastric tube and nasogastric tube
  orogastric tube in period 1 and nasogastric tube in period 2

Первичные конечные точки

• Compare impact of insertion site of gastric tube on the incidence of ventilator associated pneumoniae [Срок оценки: Day 28]

Критерии участия

Критерии включения

• patient in intensive care, intubated, ventilated
• Adult
• Requiring a gastric tube
• With an expected duration of mechanical ventilation of more than 48 hours
• Affiliated to social security
• Patient or relative consent or, failing that, emergency inclusion of the patient

Критерии исключения

• Pregnant, breast-feeding or parturient women
• Patients under legal protection: curatorship and guardianship
• Contraindication to placing a gastric tube through the nose or mouth
• Patients who already have a gastric tube when they enter the service
• Patient intubated for more than 24 hours
• Patient intubated via the nasotracheal route

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Перекрёстный дизайн

Маскирование

Открытое

Основная цель

Другое

Центры проведения

Франция · 1 центр

• Centre Hospitalier Du Mans — Le Mans

Публикации

• Saletes J, Guitton C, Valleroy J, Guillarme S, Haubertin C, Paris G, Muller L, Rousseau C, Gamon P, L'Hotellier S, Forel JM, Roussel C, Garin A, Morand C, Maury E, Mangeard N, Menard L, Arnaud PY, Lejeune A, Rouanet E, Callahan JC. Effect of nasogastric versus orogastric tube placement on ventilator-associated pneumonia incidence in critically ill patients: a study protocol for a cluster randomise PMID 40921641

Идентификаторы

NCT: NCT05915663 · CHM-2022/S03/05

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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