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Идёт набор NCT05898594

Lung Cancer Screening in High-risk Black Individuals

Без фазы С лечением Lung Cancer Lung Carcinoma

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Low-dose Computed Tomography.
Кому может быть актуально
Состояния в реестре: Lung Cancer, Lung Carcinoma. Базовые параметры: 50 лет — 80 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
США
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Evaluating the Feasibility of Lung Cancer Screening in High-risk Black Individuals

Обзор

The goal of this research study is to study U.S. Black individuals with a history of smoking to examine the feasibility, acceptability, and performance of low-dose computed tomography (LDCT) screening among this population. The name of the intervention used in this research study is: Low-dose computed tomography (radiologic scan) chest scan

Подробное описание

The goal of this single-arm pilot research study is to evaluate the feasibility and acceptability of low-dose computed tomography (LDCT) screening for lung cancer among U.S. Black individuals with a history of smoking.

LDCT screening is currently the only recommended way to screen for lung cancer among high-risk individuals. However, many Black individuals at high-risk for lunch cancer are currently ineligible for lung cancer screening.

Study procedures include screening for eligibility, completion of questionnaires, and a LDCT screening test.

Participation in this study is expected to last up to 3 months.

It is expected about 900 people will participate in this study.

Вмешательства

  • Процедура Low-dose Computed Tomography
    Per standard care

Первичные конечные точки

  • Proportion of Enrolled Participants [Срок оценки: At enrollment]
  • Proportion of Participants with Positive Low-dose Computed Tomography Test [Срок оценки: At 3 months]
  • Proportion of Participants Diagnosed with Invasive Lung Cancer [Срок оценки: At 6 months]
  • Distribution of Lung Imaging Reporting and Data System (Lung-RADS) Scores [Срок оценки: At 3 months]
Вторичные конечные точки (2)
  • Proportion of Participants Who Undergo Invasive Diagnostic Procedures [Срок оценки: At 6 months]
  • Proportion of Participants Who Have a Complication Resulting from an Invasive Diagnostic Procedure Performed for a Positive Low-dose Computed Tomography Scan [Срок оценки: At 6 months]

Критерии участия

Критерии включения

  • Self-identified Black individual.
  • Have a self-reported history of smoking. No restriction will be placed on the number of smoking pack years participants must have nor the number of years former smokers must have quit smoking.
  • Aged 50-80 years.

Критерии исключения

  • Individuals with a history of lung cancer.
  • Individuals with symptoms suggestive of lung cancer. We will evaluate whether individuals have symptoms suggestive of lung cancer by administering an online screening questionnaire, which will ask whether they have experienced shortness of breath, whether they become easily winded, and whether they have had a chronic cough within the last 12 weeks that has not improved. Individuals who select that they have any one of these symptoms will be advised to follow up with their primary doctor and will not be eligible to participate in the study.
  • Individuals with pneumonia or acute respiratory infection within 12 weeks prior to enrollment that was treated with antibiotics.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Не применимо
Модель
Одна группа
Маскирование
Открытое
Основная цель
Скрининг

Центры проведения

США · 2 центра
  • University of Chicago — Chicago
  • Massachusetts General Hospital Cancer Center — Boston

Идентификаторы

NCT: NCT05898594 · 22-382 · 1R18HS029430-01

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗