Reciprocal Imitation Training and Musical Rhythm Sensitivity in Autistic Toddlers

Официальное название

Musical Rhythm Sensitivity to Scaffold Social Engagement in Autism Spectrum Disorder

Обзор

The primary goal of this study is to examine rhythm sensitivity as a predictor of response to naturalistic developmental behavioral intervention (NDBIs) in autistic toddlers. Toddlers receive either Reciprocal Imitation Training (RIT), an evidence-based NDBI that supports children's imitation and social communication skills, or a music-enhanced version of RIT. Throughout their participation in the intervention, toddlers will complete study procedures of viewing naturalistic videos of infant-directed singing and other social scenes while eye gaze data is collected.

Подробное описание

Social communication makes use of predictable, rhythmic behaviors and children are sensitive to the rhythm of social interaction from infancy. The goal of the current study is to investigate if social rhythm sensitivity, measured via children' entrained eye-looking when viewing videos of infant-directed singing, predicts autistic toddlers' response to naturalistic developmental behavioral intervention (NDBI). Following eligibility testing and baseline assessments, children are randomized to receive either 30 sessions of Reciprocal Imitation Training (RIT), an NDBI that uses evidence-based strategies to support children's imitation and social communication development, or a music-enhanced version of RIT that embeds music and rhythm within the RIT platform (meRIT). Children's imitation skills are assessed before and after the intervention programs. Children's rhythm sensitivity is assessed via repeated eye-tracking sessions throughout baseline, intervention, and two-weeks after the intervention ends.

Вмешательства

• Поведенческое Reciprocal Imitation Training
  As a naturalistic developmental behavioral intervention (NDBI), Reciprocal Imitation Training (RIT) utilizes contingent imitation, linguistic mapping, modeling, prompting, and contingent reinforcement to train object and gesture imitation during play activities.
• Поведенческое music-enhanced Reciprocal Imitation Training
  Music-enhanced imitation training uses music and rhythm to enhance the predictability and salience of the strategies utilized within the Reciprocal Imitation Training platform (i.e., contingent imitation, linguistic mapping, modeling, prompting, and contingent reinforcement to train object and gesture imitation during play activities).

Первичные конечные точки

• Change in rhythmically entrained eye-looking (eye-tracking) [Срок оценки: Change from baseline through 2-week follow-up post-intervention]

Вторичные конечные точки (3)

• Change in overall fixation to eyes (eye-tracking) [Срок оценки: Change from baseline through 2-week follow-up post-intervention]
• Change in child elicited motor imitation [Срок оценки: Change from baseline to 2-weeks follow-up after intervention]
• Change in child spontaneous motor imitation [Срок оценки: Change from baseline to 2-weeks follow-up after intervention]

Критерии участия

Критерии включения

• diagnosis of autism / autism spectrum disorder
• 18-36 months of age

Критерии исключения

• Major hearing or visual impairment (e.g., congenital nystagmus), seizure disorder, genetic syndromes, or gestational age <=34 weeks.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Простое слепое

Основная цель

Лечение

Центры проведения

США · 1 центр

• Vanderbilt University Medical Center — Nashville

Идентификаторы

NCT: NCT05880225 · MH123029

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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