Effects of Omega-3 and Whey Protein Supplementation on Lean Mass in Older Adults

Официальное название

Effects of Omega-3 and Whey Protein Supplementation on Lean Mass and Strength Gains in Older Adults Performing Resistance Exercise: A Randomized, Double-Blind and Placebo-Controlled Study

Обзор

To evaluate the effect of omega-3 supplementation combined with whey protein intake on lean mass and strength gains in older adults performing resistance exercise. Participants will be randomized into the 4 groups. The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin. The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin. The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil. The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein. All will perform the same exercise protocol for 12 weeks

Вмешательства

• Пищевая добавка Placebo Group
  The placebo group will receive 4 g per day of corn oil and 40 g per day of maltodextrin.
• Пищевая добавка Whey Protein + Placebo
  The whey protein + placebo group will receive 40g per day of whey and 4g per day of corn oil.
• Пищевая добавка Omega 3 + Placebo
  The omega 3 + placebo group will receive 4 g per day of fish oil and 40 g per day of maltodextrin.
• Пищевая добавка Omega 3 + Whey Protein
  The omega 3 + whey group will receive 4g per day of fish oil and 40g per day of protein.

Первичные конечные точки

• Changes in lean mass (kg) using ultrasound and electrical bioimpedance in postmenopausal women [Срок оценки: up to 12 weeks]

Вторичные конечные точки (1)

• Changes in strength (kg) using dynamometer in postmenopausal women [Срок оценки: up to 12 weeks]

Критерии участия

Критерии включения

• Postmenopausal women (at least 1 year of menstrual interruption, self-reported);
• To be able to practice strength exercises;
• To be able to carry out supplementation;
• Do not present physical, orthopedic or cardiovascular complications that prevent the performance of physical exercises;
• No history of stroke or acute myocardial infarction;
• Not being a smoker and/or alcoholic;
• Do not perform hormone replacement therapy;
• Do not use anti-inflammatory drugs;
• To have normal kidney function;
• To submit a medical certificate of health that proves that the individual is able to perform exercises.

Критерии исключения

• Do not provide the necessary information for the development of the study;
• Individuals with diseases previously diagnosed and undergoing treatment, such as type II diabetes mellitus, cancer, rheumatoid arthritis, high blood pressure, dyslipidemia, cardiovascular, and kidney and/or liver diseases.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение

Рандомизированное

Модель

Параллельные группы

Маскирование

Тройное слепое

Основная цель

Профилактика

Центры проведения

Бразилия · 1 центр

• Federal University of Uberlandia — Uberlândia

Идентификаторы

NCT: NCT05862779 · 5.728.049

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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