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Идёт набор NCT05819996

Addressing Tetrachloroethylene Exposure in an Impacted Community

Без фазы С лечением Vapors; Inhalation Cancer Volatile Organic Compounds

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Environmental educational campaign.
Кому может быть актуально
Состояния в реестре: Vapors; Inhalation, Cancer, Volatile Organic Compounds. Базовые параметры: 18 лет — 99 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
США
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Официальное название

Addressing Tetrachloroethylene Exposure in an Impacted Community: Residents' Concerns, Neurotoxic Effects, and Exposure Reduction

Обзор

Groundwater in Martinsville, IN, is contaminated by volatile organic compounds (VOCs), tetrachloroethylene (PCE) and trichloroethylene (TCE). Indoor air in some residential and commercial buildings is also contaminated with PCE and TCE. This study is being conducted to better understand the impact of low-level exposures to these compounds on community members' health. Data collected in this study will be used to help the community identify a course of action.

Подробное описание

Martinsville, IN, is a community of 11,000 people that overlays four groundwater contamination sites, including a U.S. Environmental Protection Agency (EPA)-designated Superfund site. The total area of groundwater contamination is over 60 acres and lies within a single aquifer. The contaminates are chlorinated volatile organic compounds (VOCs), primarily tetrachloroethylene (PCE) and trichloroethylene (TCE). These contaminants are thought to originate from several dry cleaning and metal degreasing operations. An activated carbon filtration system has been in operation since 2005 to remove PCE and chlorinated VOCs from the municipal water, which now meets EPA drinking water standards. However, a recent report from the Agency for Toxic Substances and Disease Registry concludes that people's health may be harmed by breathing indoor air contaminated via vapor intrusion, the migration of volatile compounds from contaminated groundwater and soil into buildings above. The long-term goal of this research is to understand how PCE exposure in communities affects health and to empower community members' participation in environmental health decision-making. In this project researchers will work with the community of Martinsville, IN to:

1. Determine the extent and exposure levels to the contaminants by measuring the contamination in residents and at their homes. 2. Assess the community's concern and perceptions about the contamination and associated health risks. 3. Study the impact of the contaminants on visual and neurocognitive functions. 4. Compare cancer rates in Martinsville to county and state rates.

The above information will help researchers and community partners co-design a targeted educational campaign to reduce community members' exposure to the contaminants.

Вмешательства

  • Поведенческое Environmental educational campaign
    Educational campaign will be conducted to promote participation in indoor air testing.

Первичные конечные точки

  • Change in concerns about environmental chemical contamination in Martinsville. [Срок оценки: For Measure 1a, Time frame is from year 1 to year 3; for Measure 1b, Time frame is from year 1 to year 5.]
  • Changes in awareness of possible exposure to chemicals from soil or groundwater in Martinsville. [Срок оценки: For Measure 2a, Time frame is from year 1 to year 3; for Measure 2b, Time frame is from year 1 to year 5.]
  • Change in willingness to have respondent's homes tested for chemical contamination from contaminated soil or groundwater. [Срок оценки: For Measure 3a, Time frame is from year 1 to year 3; for Measure 3b, Time frame is from year 1 to year 5.]

Критерии участия

Критерии включения

  • Residents of Martinsville, Indiana
  • 18 years or older

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Распределение
Не применимо
Модель
Одна группа
Маскирование
Открытое
Основная цель
Другое

Центры проведения

США · 1 центр
  • Purdue University — West Lafayette

Идентификаторы

NCT: NCT05819996 · 20211507

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗