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Идёт набор NCT05759143

Enhancing Information Management for Young Adults After Genetic Cancer Risk Testing

Без фазы С лечением Genetic Predisposition to Disease Genetic Predisposition

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: Nest Platform.
Кому может быть актуально
Состояния в реестре: Genetic Predisposition to Disease, Genetic Predisposition. Базовые параметры: 18 лет — 39 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
США
Следующий шаг
Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Обзор

This research is being done to develop the electronic platform Nest for young adults (ages 18-39) who have had prior cancer genetic testing. The platform will give patients and their clinicians access to continuously updated information about both pathogenic variants and variants of uncertain significance (VUS). The name of the intervention used in this research study is: Nest portal (electronic platform for patients and clinicians)

Подробное описание

The goal of the electronic platform Nest is to help patients understand and manage genetic test results and recommended care and to help clinicians with access to results and recommendations, facilitating orders, and documentation. The portal has two parts, one for participants and one for clinicians.

For the first phase of the study, participants will give their feedback on the Nest portal's content and processes that will guide refinement of the portal. The Pilot phase will test the feasibility and acceptability of the intervention.

The research study procedures include a baseline survey, using the portal after receiving a brief orientation from the study team, a follow-up survey, and then a 30-minute interview.

Participants will be in this research study for up to 2 hours.

It is expected that about 40 people will take part in this research study.

The electronic platform is being developed by Nest Genomics.

Вмешательства

  • Поведенческое Nest Platform
    Patient- and clinician-facing portal via secure link

Первичные конечные точки

  • Proportion of Participant Utilization (Feasibility) [Срок оценки: 2 hours]
  • Proportion of Clinician Utilization (Feasibility) [Срок оценки: 2 hours]
  • Proportion of Clinicians with FIM (Feasibility of Intervention Measure) Score > 4 [Срок оценки: At post-visit survey, up to 2 hours]
  • Proportion of Participants with AIM (Acceptability of Intervention Measure) Score > 4 [Срок оценки: At post-visit survey, up to 30 days]
  • Proportion of Clinicians with AIM Score > 4 [Срок оценки: at post-visit survey, up to 2 hours]
Вторичные конечные точки (2)
  • Change in knowledge of cancer risk [Срок оценки: Baseline and post visit up to 2 hours]
  • Change in Recommended screening [Срок оценки: Baseline and post visit up to 2 hours]

Критерии участия

Inclusion Criteria AIM 1:

  • YA Patients:
  • Ages 18-39 years, inclusive.
  • Has had previous cancer genetic testing, with a finding of a pathogenic variant or VUS; patient has previously received results from the clinical team.
  • English-speaking and -reading.
  • Receiving care at DFCI.
  • Not undergoing active cancer therapy at the time of approach.
  • Clinicians:
  • Cancer risk physicians (oncologists, gastroenterologists, geneticists), oncologists, nurse practitioners, physician assistants, or genetic counselors.
  • English-speaking and -reading.
  • Cares for YAs aged 18-39 with cancer risk syndromes.

Inclusion Criteria AIM 2:

  • YA Patients:
  • Ages 18-39 years, inclusive.
  • Has had previous cancer genetic testing, with a finding of a pathogenic variant or VUS; patient has previously received results from the clinical team.
  • English-speaking and -reading.
  • Receiving care at Dana-Farber Cancer Institute.
  • Did not participate in a stakeholder interview (Aim 1).
  • Not undergoing active cancer therapy at the time of approach.
  • Clinicians:
  • Oncologists, nurse practitioners, cancer risk physicians, or genetic counselors.
  • English-speaking and -reading.
  • Caring for a participating YA.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Да

Дизайн исследования

Распределение
Нерандомизированное
Модель
Одна группа
Маскирование
Открытое
Основная цель
Организация здравоохранения

Центры проведения

США · 1 центр
  • Dana Farber Cancer Institute — Boston

Идентификаторы

NCT: NCT05759143 · 22-657

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗