Идёт набор NCT05750147

The SMARTER Cardiomyopathy Study

— Наблюдательное Cardiomyopathies Hypertrophic Cardiomyopathy Dilated Cardiomyopathy

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: Blood Sample Collection.
Кому может быть актуально: Состояния в реестре: Cardiomyopathies, Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy. Базовые параметры: Без ограничений · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: Великобритания
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

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Официальное название

Genetics, Imaging and Artificial Intelligence for Precision Care in Cardiomyopathy

Обзор

Cardiomyopathies are diseases of the heart muscle. Known genetic factors may account for some cardiomyopathy cases but there is still much to understand about the genetic and environmental causes and how the disease progresses. Finding new ways to diagnose and treat cardiomyopathies could improve the health and well-being of patients with these conditions. This study will collect data from individuals with cardiomyopathy or related heart muscle disease, or with a possible genetic predisposition to cardiomyopathy, and follow them over time to observe the progress of their heart and health. This study will collect DNA, blood samples, and detailed clinical \& lifestyle information at the start of the study, and data collected during routine healthcare visits over time. * learn what causes cardiomyopathy, and therefore how to treat it * understand why cardiomyopathy progresses differently in different people, to improve the ability to recognise who will benefit from different treatments at different times The investigators will collaborate with other centres internationally to collect a large of group of participants with similar cardiomyopathies, providing power to identify new pathways that cause disease and ways of predicting which participants are at risk of having more severe disease.

Вмешательства

Другое Blood Sample Collection
Blood for DNA and biomarker analysis

Первичные конечные точки

Incidence of genetic variants [Срок оценки: 5 years]
The incidence of major adverse cardiovascular events over 5 years [Срок оценки: 5 years]

Критерии участия

Критерии включения

Adults with the capacity to consent Children with parental/guardian consent Male and Female

Meeting the following criteria:

Patients with a confirmed diagnosis of cardiomyopathy or related condition
Patients with a family member with cardiomyopathy, or a related condition
Patients with a genetic variant that may predispose to cardiomyopathy, or a related condition