CLABSI Prevention With Tissue Adhesive

Health-care associated infections (HAI) and especially central-line associated blood stream infections (CLABSI) are a well described burden in the intensive care units. There are two main possible pathways leading to central-venous line (CVL) related infection: the first is migration of microbes down the catheter tract (between the CVL and the skin), and the second is via the catheter hub/lumen. Cyanoacrylate adhesive is a commonly used tissue adhesive in children and adults with frequent use in pediatric facial lacerations. Several studies have shown its feasibility and safety in the general pediatric population, including neonates and in children after cardiac surgery.

To our knowledge, no study to date has explored the use of 2-octyl cyanoacrylate at central-line exit site as a mean to decreases pediatric CLABSI.

Our aim is to assess 2-octyl cyanoacrylate association with CLABSI rate in pediatric cardiac intensive care population.

• dressing changes rates [Срок оценки: average of 14 days]
• safety outcome: Number pf participants with contact dermatitis at the catheter exit site, line dislodgement, leak, exit site bleeding, allergic reaction or line tunnel infection [Срок оценки: average of 14 days]
• invasive mechanical ventilation duration [Срок оценки: up to 1 year]
• ICU LOS [Срок оценки: up to 1 year]
• Postoperative ECMO support [Срок оценки: up to 1 year]
• Chylothorax [Срок оценки: up to 1 year]
• Chest drains duration [Срок оценки: up to 1 year]
• need for cardiopulmonary resuscitation (CPR) [Срок оценки: up to 1 year]
• Extubation failure [Срок оценки: up to 1 year]
• presence of lung atelectasis [Срок оценки: up to 1 year]
• multidrug resistant bacterial colonization [Срок оценки: up to 1 year]
• mortality rate [Срок оценки: up to 1 year]