Personalized Mobile Cognitive Behavioral Therapy Application

Growing evidence suggests a need for anxiety and mood interventions that can be disseminated easily to adolescents and young adults. The goal of this study is to optimize a mobile application that teaches well-established, research-supported psychotherapeutic techniques to adolescents and young adults who are experiencing symptoms of anxiety, depression, and/or bipolar disorder. The study aims to compare the efficacy of a personalized mobile cognitive behavioral therapy program to a more general mobile cognitive behavioral therapy program.

Study participants will randomly receive one of two versions of Maya, a mobile cognitive behavior therapy (CBT) app for adolescents and young adults: either a standard version that includes a variety of skills typically used in CBT, or a personalized version with skills matched to the participant's symptom profile. In contrast to the general condition, which may introduce new material over all six weeks of the intervention, all new material in the personalized condition will be introduced within the first four weeks. The remaining two weeks in the personalized condition will consist of practicing previously learned skills. Participants will use the Maya app for two days per week, at least 20 minutes per day for six weeks and will complete assessments at baseline, week 4, week 6 (end of intervention), and a follow-up assessment at week 12. Participants may also choose to complete an optional electroencephalographic (EEG) recordings at the baseline and end of intervention (week 6).

• Change in anxiety measure scores pre-intervention to post-active learning phase as measured by HAM-A [Срок оценки: Baseline to end of active learning phase [week 4]]
• Change in anxiety measure scores pre-intervention to post-active learning phase as measured by the anxiety subscale of the DASS. [Срок оценки: Baseline to end of active learning phase [week 4]]
• Change in depression measure scores pre-intervention to post-active learning phase as measured by HAM-D. [Срок оценки: Baseline to end of active learning phase [week 4]]
• Change in depression measure scores pre-intervention to post-active learning phase as measured by the depression subscale of the DASS. [Срок оценки: Baseline to end of active learning phase [week 4]]
• Change in social anxiety from pre-intervention to post-intervention as measured by LSAS. [Срок оценки: Baseline to end of active learning phase [week 4 for personalized intervention and week 6 for the general intervention]]
• Change in anxiety sensitivity from pre-intervention to post-intervention as measured by ASI. [Срок оценки: Baseline to end of active learning phase [week 4 for personalized intervention and week 6 for the general intervention]]
• Change in avoidance from pre-intervention to post-intervention as measured by MEAQ. [Срок оценки: Baseline to end of active learning phase [week 4 for personalized intervention and week 6 for the general intervention]]
• Change in anhedonia from pre-intervention to post-intervention as measured by TEPS. [Срок оценки: Baseline to end of active learning phase [week 4 for personalized intervention and week 6 for the general intervention]]
• Change in Negative affect from pre-intervention to post-intervention as measured by PANAS [Срок оценки: Baseline to end of active learning phase [week 4 for personalized intervention and week 6 for the general intervention]]
• Bipolar symptoms from pre-intervention to post-intervention as measured by ISS. [Срок оценки: Baseline to end of active learning phase [week 4 for personalized intervention and week 6 for the general intervention]]