The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability.
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: no intervention.
- Кому может быть актуально
- Состояния в реестре: Dry Eye. Базовые параметры: 20 лет — 35 лет · Женщины.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
The Effect of Eyeliner on Tear Composition, Tear Secretion and Tear Film Stability：a Prospective Cohort Study.
Обзор
Eyeliner is one of the most common eye cosmetics. The main ingredients are titanium oxide, pigment, grease and preservative. The user will apply the eyeliner to the eyelid and eyelash. With the blinking again and again, the components of the eyeliner may enter the tear film and continue to act on the eye surface. Therefore, the investigators suspect that the use of eyeliner may be an important factor leading to dry eye disease. In order to explore the relationship between the use of eyeliner and dry eye disease, the investigators plan to collect eye surface characteristic data of the two groups of people who use eyeliner and who do not use it.Then use Raman analysis to explore whether the use of eyeliner will lead to changes in tear composition.The investigators intend to analyze the difference of tear composition between the two groups to understand the relationship between the change of tear composition and tear film stability.So that the investigators can identify the risk factors of dry eye disease, and provide basis for prevention and early treatment.
Подробное описание
The investigators will include the population according to the inclusion criteria and exclusion criteria.The subjects in the eyeliner group and the control group filled in the survey to score the ocular surface disease index. Tear secretion test and sodium fluorescein staining are conducted in the eyeliner group and the control group, and the results are recorded. The intraocular pressure of the two groups is measured and recorded. Dry eye analysis is conducted for the two groups of people to collect relevant data. Tears are collected by capillary glass tube and stored for further Raman analysis.
Вмешательства
- Другое no intervention
no intervention
Первичные конечные точки
- The Schirmer's test evaluates aqueous tear production. [Срок оценки: baseline]
- The gland loss assessed by meibography images. [Срок оценки: baseline]
- Evaluation of lipid content and ionic composition in tears by raman analysis. [Срок оценки: baseline]
Критерии участия
Критерии включения
- People aged 20-35 who use eyeliner or do not use eyeliner .
- People who use eyeliner have used it for ≥ 1 year; Frequency ≥ 3 times/week.
Критерии исключения
- Other serious systemic diseases.
- Other systemic diseases related to ocular surface, such as rheumatoid arthritis, systemic lupus erythematosus, Sjogren's syndrome and other immune system diseases or other eye diseases, history of eye surgery and trauma.
- Lactating women or pregnant women.
- Use electronic products for more than 4 hours every day.
- Patients with circadian rhythm disorder.
- People with radiation exposure history.
- Non permanent residents in Wuhan.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- Zhongnan Hospital of Wuhan University — Ухань
Идентификаторы
NCT: NCT05632887 · 20220920E