Идёт набор NCT05468255

The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults

Без фазы С лечением Glucose Intolerance Exercise Vascular Function

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают: В протоколе указаны: removal of exercise.
Кому может быть актуально: Состояния в реестре: Glucose Intolerance, Exercise, Vascular Function. Базовые параметры: Без ограничений · Все.
Что важно проверить: Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится: США
Следующий шаг: Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →

Не всё понятно в терминах? Прочитайте наш гид для пациентов →

Официальное название

The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active

Обзор

The purpose of this study is to determine if an acute bout of removal of exercise reduces enothelial function and glycemic control in an active, older adult population; and whether a 3 day return to exercise restores this response. Glycemic control is the blood glucose response following the consumption of a meal. It is an indicator of insulin resistance (or type 2 diabetes) and impaired glycemic control has been suggested to lead to cardiovascular disease. Endothelial function has been shown to be improved by chronic or acute increases in physical activity. Both of these have been shown to be impaired to acute bouts of inactivity in young populations; however the impact of acute inactivity in older adults is less understood. In this proposal the investigators will examine 1)how quickly impairments in glycemic control occur to acute physical inactivity in older adults who exercise, 2) how quickly impairments in endothelial function occur to acute inactivity in older adults who exercise, and 3) whether 3 days of a return to exercise restores these responses.

Вмешательства

Другое removal of exercise
Subjects will stop doing their normal exercise routines for 3 or 5 days and then subjects will resume doing their normal exercise routines for 3 days.

Первичные конечные точки

Continuous glucose monitoring [Срок оценки: 3 days before removal of exercise]
Continuous glucose monitoring [Срок оценки: After removal of exercise for 5 days]
Continuous glucose monitoring [Срок оценки: After return to exercise for 3 days]
Flow mediated dilation [Срок оценки: 3 days before removal of exercise]
Flow mediated dilation (vascular health) [Срок оценки: After removal of exercise for 5 days]
Flow mediated dilation (vascular health) [Срок оценки: After return to exercise for 3 days]

Критерии участия

Критерии включения

55 years and older, 18-40 years old
Healthy, physically active, performing at least 90 min/week of physical activity
Free of physical limitations that may interfere with alterations in daily physical activity levels