Adapted Physical Activity for Children Treated With Cancer and Insulin Sensitivity
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Adapted Physical Activity Strong.
- Кому может быть актуально
- Состояния в реестре: Pediatric Cancer. Базовые параметры: 5 лет — 18 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Франция
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Обзор
The main objective of this study is to evaluate the evolution of the sensitivity to insulin, a hormone that acts on sugar in the body, as well as other metabolic, motor and nutritional elements of children with cancer, according to the practice of intense physical activities or stretching. In view of the scientific work on this subject, it is expect to observe that the practice of intense physical activities will improve the results of the children in the metabolic, motor and nutritional evaluations, compared to the stretching program.
Подробное описание
The protocol consists of 6 months of intense physical activity and stretching programs for children with solid cancer or haematological disease, starting at diagnosis. Evaluations will be performed at the first, third and sixth month of the programs and then six and eighteen months after they are stopped. The physical activity sessions will take place in the hospital during hospitalizations or by videoconference when the children are at home. The sessions are adapted to the needs, desires and abilities of the children and will take place two to three times a week. They will be mediated by various activities such as soccer, rugby, darts, muscle strengthening. Inclusion lasts two years.
Вмешательства
- Другое Adapted Physical Activity Strong
Children will practice physical activities combining aerobics and muscle strengthening. They will follow a 30-minute (for prepubescent children) or 60-minute (for pubescent children) Strong adapted physical activity session 2 to 3 times a week during hospitalization periods or by videoconference at home when they are not hospitalized.
Первичные конечные точки
- Insulin Sensitivity [Срок оценки: 6 months]
Критерии участия
Критерии включения
- age between 5 and 18 years old;
- have a solid cancer or hematological disease;
- be treated for the first time in pediatric oncology and hematology department;
- have an estimated life expectancy at diagnosis of more than 6 months.
Критерии исключения
- present a physical and/or psychological impossibility to follow an adapted physical activity program;
- have a pre-existing heart disease that is not suitable for adapted physical activities;
- have a known type 1 diabetes
- have an obesity defined by a body mass index greater than or equal to the International Obesity Task Force 25 threshold
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Открытое
- Основная цель
- Поддерживающая терапия
Центры проведения
Франция · 1 центр
- PASQUET Marlène — Toulouse
Публикации
- Thomas J, Filleron T, Auriol F, Laurens C, Pasquet M. Study protocol of an early randomized intervention trial assessing the metabolic effects of two levels of exercise intensity in children undergoing cancer treatment: the APACIS study. BMC Cancer. 2025 May 9;25(1):850. doi: 10.1186/s12885-025-14235-4. PMID 40346598
Идентификаторы
NCT: NCT05383092 · RC31/22/0061