The Dampness Syndrome of Chinese Medicine Cohort Study
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: natural aging process.
- Кому может быть актуально
- Состояния в реестре: Chronic Disease, Cancer, Dementia Alzheimers, Metabolic Disease. Базовые параметры: 35 лет — 79 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Китай
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
Не всё понятно в терминах? Прочитайте наш гид для пациентов →
Официальное название
A Multi-Center Prospective Cohort Study of Dampness Syndrome in China
Обзор
The researchers plain to build a large-scale, longitudinal, prospective cohort characterized by TCM dampness syndrome. With the biobank of this cohort the investigators want to find the causality between TCM dampness syndrome and clinical chronic diseases and a new way to treat clinical disease.
Подробное описание
DACOS is a national large- scale, longitudinal, multi-center, prospective, cohort study of natural person aged 35 to 75. The baseline survey and the follow-up surveys will be conducted in 5 areas covering the eastern, northern, western, southern and middle parts of China. In this study 100,000 natural person will be regularly followed up for 5 years(visited once a year), with the loss rate ≤15%. Three parts will be carried in the form of interview, physical examination and biological sample collection. During the interview, the investigators plan to do some questionnaires to learn participants' demographic characteristics, life style, disease history, healthy condition(EQ-5D-5L, SDS,), cognition state(AD-8, MMSE, MoCA) and the results of TCM syndrome differentiation(Score of Dampness syndrome and TCM constitution scale). All biological specimens (including blood, feces, urine, saliva and tongue coating) will be collected and stored in the biological resource center until researchers request their use. With the building up of this cohort, the researchers will analyze the causality between dampness syndrome and specific chronic diseases such as diabetes, coronary heart disease, cancer, dementia and so on.
Вмешательства
- Другое natural aging process
To observe the relationship between new cases of diseases and health status of people exposed to different factors such as life style, alcohol consumption, eating habits, etc.
Первичные конечные точки
- emerging diseases [Срок оценки: through study completion, an average of 1 year]
Вторичные конечные точки (12)
- Montreal Cognitive Assessment(MoCA) [Срок оценки: through study completion, an average of 1 year]
- European Quality of Life 5-dimensional questionnaire (EQ-5D-5L) [Срок оценки: through study completion, an average of 1 year]
- Mini-Mental State Exam (MMSE) [Срок оценки: through study completion, an average of 1 year]
- interview questionnaire [Срок оценки: through study completion, an average of 1 year]
- change of the blood routine results [Срок оценки: through study completion, an average of 1 year]
- urine routine [Срок оценки: through study completion, an average of 1 year]
- change of faeces routine [Срок оценки: through study completion, an average of 1 year]
- change of hepatic function [Срок оценки: an average of 1 year]
- change of renal function [Срок оценки: an average of 1 year]
- change of CRP [Срок оценки: an average of 1 year]
- change of Hcy [Срок оценки: an average of 1 year]
- change of thyroid function [Срок оценки: an average of 1 year]
Критерии участия
Критерии включения
- Residents aged 30 to 79, whose residence is consistent with their registered permanent residence location;
- Residents who voluntarily participate in the project, agree to the collection of their biological information, and sign the informed consent form;
- Residents who have no mental illness and other related diseases, and display a normal ability of expression and understanding;
Критерии исключения
- Residents who reject collaboration;
- Residents who allow no follow-up visits.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Да
Дизайн исследования
- Модель наблюдения
- Когортное
Центры проведения
Китай · 1 центр
- Guangdong Province Hospital of Tradtional Chinese Medicine — Гуанчжоу
Публикации
- Li M, Liu N, Jiang G, Zeng H, Guo J, Wu D, Zhou H, Wen Z, Zhou L. Health-related quality of life in populations with diabetes, prediabetes, and normal glycemic levels in Guangzhou, China: a cross-sectional study. Front Endocrinol (Lausanne). 2025 May 23;16:1518204. doi: 10.3389/fendo.2025.1518204. eCollection 2025. PMID 40487765
Идентификаторы
NCT: NCT05315895 · SZ2021ZZ06