A Study to See if an iPhone Weight Management App Can Help Promote Weight Loss in Adolescents and Young Adults After a Stem Cell Transplant

PRIMARY OBJECTIVE:

I. To evaluate the effectiveness of an addiction-based weight loss intervention, embodied as a smartphone application (app) with telephone coaching, on weight outcomes of overweight and obese post hematopoietic stem cell transplantation (HSCT) adolescents and young adults.

SECONDARY OBJECTIVES:

I. To evaluate the changes in metabolic parameters and physical activity levels, in addition to modifications in addictive eating behaviors, motivation, and self-regulatory behaviors.

II. To evaluate the feasibility, adherence, and satisfaction of this intervention.

OUTLINE:

Patients receive an iPhone with W8Loss2Go app, a body scale and a digital food scale to weigh themselves and food daily. Patients interact with coaches via text messages for 4 days weekly and receive weekly 15 minute phone calls for appointment reminders, emotional support, progress discussion, and follow up on items discussed in a prior visit or phone call. Patients also have telemedicine interviews with the coach lasting 60 minutes at 2 and 4 months to elicit both positive and negative impacts on weight management and to identify barriers such as emotional eating, displacement behaviors, poor coping skills to life stressors, and social challenges. Patients who opt to extend the intervention until month 12 attend an additional telemedicine meeting with the coach. Patients also complete questionnaires over approximately 1.5 hours.

• Adherence [Срок оценки: Up to 12 months]
• Fasting lab test analysis: HbA1c [Срок оценки: At four months up to 12 months]
• Fasting lab test analysis: Total cholesterol [Срок оценки: At four months up to 12 months]
• Fasting lab test analysis: Low density lipoprotein [Срок оценки: At four months up to 12 months]
• Fasting lab test analysis: High density lipoprotein [Срок оценки: At four months up to 12 months]
• Fasting lab test analysis: triglycerides [Срок оценки: At four months up to 12 months]
• Fasting lab test analysis: aspartate/alanine aminotransferase [Срок оценки: At four months up to 12 months]
• Fasting lab test analysis: glucose [Срок оценки: At four months up to 12 months]
• Yale Food Addiction Scale [Срок оценки: Up to 12 months]
• Center for epidemiologic studies depression scale [Срок оценки: Up to 12 months]
• Perceived stress scale [Срок оценки: Up to 12 months]
• Satisfaction with program [Срок оценки: Up to 12 months]