Sensory-Motor Integration for Speech Rehabilitation in Patients with Post-stroke Aphasia
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: Enriched rehabilitation, Simple rehabilitation.
- Кому может быть актуально
- Состояния в реестре: Aphasia Non Fluent, Stroke. Базовые параметры: 55 лет — 75 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- Франция
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
Evaluation of an Enriched Speech Rehabilitation Program Combining Speech Therapy and Sensory-motor Integration in Aphasic Patients
Обзор
SEMO is a multidisciplinary project (language sciences, cognitive psychology and neuropsychology, physical medicine and rehabilitation, neurology, speech-language pathology, functional neuroimaging and engineering sciences) that aims first, to test and develop a novel speech rehabilitation program designed for patients with non-fluent aphasia and, second, to better describe neural reorganization after successful recovery. To this end, the investigators will conduct a prospective monocentric cross-over study, including two cohorts of post-stroke aphasic patients and two control groups.
Подробное описание
In this project, the investigators propose to evaluate the effectiveness of a new rehabilitation program, based on illustration of speech articulators, to improve speech in patients with non-fluent aphasia. The instigators' method is based on the reinforcement of the interaction between perceptual and motor representations, thanks to the innovative Ultraspeech device. The investigators will exploit a fundamental psycholinguistic principle, which postulates that speech is based both on the activation of the system controlling the motricity of effectors related to word articulation (action) and on the auditory or visual representation of words (perception). The sensory-motor interaction method that the investigators propose allows the patient to perceive phonemes and visualize on a computer screen the movements of the tongue and lips previously recorded by a healthy speaker, typically a speech therapist. Through repeated exercises, the patient is trained to produce sounds correctly, using the correct pronunciation and articulatory movements of the reference speaker as a model. The investigators will compare patients who will follow a classical speech and language therapy rehabilitation program followed by an 'enriched' rehabilitation program including rehabilitation based on sensory-motor interaction associated with speech and language therapy, and vice versa. In order to judge the favorable effect of the rehabilitation program including sensory-motor integration, the following measures will be considered: (a) language skills, (b) phonemic quality, (c) inner speech abilities and (d) cognitive function. Brain language networks will be evaluated with neuroimaging.
Вмешательства
- Устройство Enriched rehabilitation
The enriched rehabilitation is based on the use of sensory-motor integration in addition to conventional speech therapy. The sensory-motor integration method is based on the Ultraspeech-player software. This software allows therapists to display movements of speech articulators (tongue and lips) recorded on a reference speaker during production of vowels or consonants (isolated or combined). Sagittal movements of the tongue are recorded using ultrasound and front views of lip movements are captu - Устройство Simple rehabilitation
The simple rehabilitation is based on conventional speech therapy. The conventional speech therapy will be provided by the speech therapist. Classically, the speech therapist uses word production with repetition and naming exercises. The therapist will show the patient series of pictures associated or not with written words, and the patient is required to name them and/or read aloud the word. In case of impossibility to perform the task, the therapist may can help the patient by using the indexi
Первичные конечные точки
- Evaluation of acoustic changes in the speech signal before and after each rehabilitation protocol [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
Вторичные конечные точки (12)
- Evaluation of changes in inner speech abilities before and after each rehabilitation protocol - Inner speech testing 1 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
- Evaluation of changes in inner speech abilities before and after each rehabilitation protocol - Inner speech testing 2 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
- Clinical language assessment 1a [Срок оценки: Baseline pre-intervention]
- Evaluation of changes in language abilities before and after rehabilitation - Clinical language assessment 1b [Срок оценки: Immediately after the first intervention; immediately after the second intervention]
- Clinical language assessment 2a [Срок оценки: Baseline pre-intervention]
- Evaluation of changes in language abilities before and after rehabilitation - Clinical language assessment 2b [Срок оценки: Immediately after the first intervention; immediately after the second intervention]
- Evaluation of changes in language abilities before and after each rehabilitation protocol - Clinical language assessment 3 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
- Clinical language assessment 4 [Срок оценки: Baseline pre-intervention]
- Evaluation of changes in language abilities before and after each rehabilitation protocol - Clinical language assessment 5 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
- Evaluation of changes in language abilities before and after each rehabilitation protocol - Clinical language assessment 6 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
- Evaluation of changes in cognitive level before and after each rehabilitation protocol - Neuropsychological assessment 1 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
- Evaluation of changes in specific executive functions before and after each rehabilitation protocol - Neuropsychological assessment 2 [Срок оценки: Baseline pre-intervention; immediately after the first intervention; immediately after the second intervention]
Критерии участия
Критерии включения
- patients with non-fluent aphasia after lesion in the dominant hemisphere for language
- native speakers of French
- normal or corrected to normal vision
- satisfying all criteria for the MRI examination
Критерии исключения
- patients with comprehension deficits, hemi-spatial neglect or upper limb apraxia
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Нерандомизированное
- Модель
- Перекрёстный дизайн
- Маскирование
- Открытое
- Основная цель
- Лечение
Центры проведения
Франция · 1 центр
- Chu Grenoble Alpes — Grenoble
Идентификаторы
NCT: NCT04433351 · 38RC20.061 · 2020-A00720-39