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Набор по приглашению NCT03927638

Differences in Sitting Versus Standing on Metabolic and Cardiovascular Measurements

— Наблюдательное Overweight and Obesity

Ориентир для пациента и семьи

Простыми словами

Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.

Что изучают
В протоколе указаны: sit/stand.
Кому может быть актуально
Состояния в реестре: Overweight and Obesity. Базовые параметры: 18 лет — 50 лет · Все.
Что важно проверить
Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
Где проводится
США
Следующий шаг
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Обзор

This investigations examined the effect that posture has on metabolic and cardiovascular measurements. Further, it will explore the potential for body weight status or physical activity to influence these relationships. All subjects will complete a seated condition and a standing condition in a counterbalanced manner.

Подробное описание

The purpose of the present study was to evaluate both metabolic and cardiovascular responses to acute bouts of computer work while sitting and standing. Cardiovascular measurements were made using continuous non-invasive blood pressure monitoring and metabolic measurements were made using indirect calorimetry. Subjects will be grouped and analyzed based upon the weight status of the subject. All subjects will complete a seated condition and a standing condition in a counterbalanced manner. Investigators hypothesize that metabolic and cardiovascular responses will be elevated in the standing condition compared to sitting.

Вмешательства

  • Поведенческое sit/stand
    Subjects will be asked to both sit and stand during a single trial.

Первичные конечные точки

  • Heart Rate [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Systolic Blood Pressure (SBP) [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Diastolic Blood Pressure (DBP) [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Oxygen Consumption [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Carbon Dioxide Production [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Ventilation [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Respiratory Exchange Ration (RER) [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
Вторичные конечные точки (8)
  • Height [Срок оценки: 1 minute]
  • Weight [Срок оценки: 1 minute]
  • Body Mass Index (BMI) [Срок оценки: 1 minute]
  • Body Composition [Срок оценки: Approximately 15 minutes]
  • Total Peripheral Resistance (TPR) [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Stroke Volume [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Cardiac Output (Q) [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]
  • Muscle Oxygen Saturation [Срок оценки: Approximately 15 minutes in each condition (sitting and standing)]

Критерии участия

Критерии включения

  • healthy adult

Критерии исключения

  • Have a history of cancer, cardiac issues, hypertension, pulmonary disease, stroke, neurological or muscular dystrophy, uncontrolled diabetes, or any life threatening chronic conditions.
  • Are currently being treated for infectious mononucleosis, hepatitis, pneumonia, or other infectious diseases.
  • Are unable or unwilling to stand in one position continuously for 15-20 minutes at a time.
  • Use nicotine products, or non-contraceptive hormonal therapy (birth control is okay).
  • Are pregnant or trying to become pregnant.
  • Are not between 18 and 50 years of age.

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Здоровые добровольцы: Нет

Дизайн исследования

Модель наблюдения
Когортное

Центры проведения

США · 1 центр
  • Montclair State University — Montclair

Публикации

  • Hosick PA, Willett JM, Matthews EL. Cardiovascular strain and metabolic rate are higher following 15 minutes of standing versus seated computer work. Eur J Prev Cardiol. 2020 Dec;27(19):2131-2133. doi: 10.1177/2047487319867402. Epub 2019 Jul 29. No abstract available. PMID 31357884

Идентификаторы

NCT: NCT03927638 · 17-18-861

Первоисточники (государственные реестры)

Открыть это исследование на ClinicalTrials.gov ↗