Post-Traumatic Stress Disorder Focused Psychodynamic Psychotherapy
Ориентир для пациента и семьи
Простыми словами
Автоматическая сводка по структурированным данным реестра. Она помогает сориентироваться, но не заменяет официальный протокол или оценку врача.
- Что изучают
- В протоколе указаны: TFPP, TAU.
- Кому может быть актуально
- Состояния в реестре: PTSD. Базовые параметры: 18 лет — 70 лет · Все.
- Что важно проверить
- Возраст, диагноз и пол — только базовые ориентиры. Предыдущее лечение, анализы и другие обязательные условия указаны ниже в критериях участия.
- Где проводится
- США
- Следующий шаг
- Сохраните исследование, покажите его лечащему врачу и уточните актуальный статус у исследовательского центра. Расходы, документы и поездка →
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Официальное название
A Pilot Randomized Controlled Trial of Trauma-Focused Psychodynamic Psychotherapy (TFPP) at the VA in Veterans With PTSD
Обзор
This is a randomized controlled trial of Trauma-Focused Psychodynamic Psychotherapy (TFPP) in comparison with TAU (at the VA) in a 2:1 ratio in 75 Veterans with PTSD who have not responded to standard treatment at the VA.
Подробное описание
Veterans with PTSD are a highly vulnerable population with tremendous disability and unmet needs. Few VA patients with PTSD now actually receive evidence-based psychotherapy because current exposure-based treatments have low uptake. The project goal is to expand the range of PTSD psychotherapy treatments available at Veterans Administration Medical Centers. This pilot trauma recovery proposal takes the next step in translating a brief efficacious psychotherapy developed and tested for panic disorder, Panic Focused Psychodynamic Psychotherapy (PFPP) for Veterans with PTSD at the VA New York Harbor Healthcare System (VA NYHHCS). PFPP was developed, manualized, and studied in RCTs over the past two decades. We hope that Trauma-Focused Psychodynamic Psychotherapy (TFPP), an adaptation of PFPP, with its high response rates in panic disorder with/without agoraphobia, and non-exposure protocol, will fill crucial gaps in Veteran care. A major challenge facing psychotherapy research is translating and implementing efficacious therapies to the community. No psychodynamic psychotherapy for anxiety or PTSD has achieved this in the US. This pilot RCT represents a paradigm shift in its approach to trauma. TFPP will be the only PTSD treatment for Veterans to incorporate Veterans' input into refinement of the treatment as this project progresses. TFPP targets aspects of traumatic experience and approaches Veterans' lives more broadly than the symptom-focused treatments the VA currently offers our traumatized Veterans.
Вмешательства
- Другое TFPP
Trauma-Focused Psychodynamic Psychotherapy - Другое TAU
treatment as usual at the VA for PTSD
Первичные конечные точки
- Change in PTSD symptoms as per DSM-5 as measured by CAPS-5 [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
Вторичные конечные точки (9)
- Change in anxiety symptoms as measured by HARS. [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Change in reflective capacity as measured by RF score. [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Change in depression symptoms as measured by HDRS. [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Change in mental and physical symptoms as measured by VR-12. [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Change in work and social adjustment as measured by WSAS. [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Change in degree of limitation in ability to work as measured by WLQ [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Childhood abuse history and trauma with CTQ [Срок оценки: baseline]
- Change in adult separation anxiety symptoms as measured by the SCI-SAS [Срок оценки: baseline, 16 weeks (termination), 3 month follow-up]
- Assessment of life events on LEC. [Срок оценки: baseline]
Критерии участия
Критерии включения
- Reporting moderate PTSD, as defined by a CAPS score of >40
- Have at least one of the following history with CPT and/or PE:
- offered and declined
- dropped out of treatment
- been determined unsuitable by their treatment team
- received treatment but continue to experience symptoms meeting entrance criteria.
- Require stabilization on psychiatric medication for 2 month period prior to entry into study to avoid confounding treatments
Критерии исключения
- Presence of SCID-5 assessed psychotic disorder, bipolar disorder, or substance use that would interfere with trial demands
- Severe suicidality that would require immediate crisis management
- Organic mental syndromes, delirium, or unstable medical conditions that would interfere with trial demands
- Inability to meet trial demands.
Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.
Здоровые добровольцы: Нет
Дизайн исследования
- Распределение
- Рандомизированное
- Модель
- Параллельные группы
- Маскирование
- Простое слепое
- Основная цель
- Лечение
Центры проведения
США · 1 центр
- VA New York Harbor Healthcare System - Manhattan Campus — New York
Публикации
- Busch FN, Milrod BL. Trauma-Focused Psychodynamic Psychotherapy. Psychiatr Clin North Am. 2018 Jun;41(2):277-287. doi: 10.1016/j.psc.2018.01.005. PMID 29739526
- Kehn M, Milrod B, Chen CK. Clinical Case of Trauma-Focused Psychodynamic Psychotherapy for a Veteran With PTSD and Race-Based Trauma. Am J Psychother. 2024 Sep 1;77(3):146-150. doi: 10.1176/appi.psychotherapy.20230040. No abstract available. PMID 39277802
Идентификаторы
NCT: NCT03755401 · 2021-13720 · 1UL1TR002384-02 · 1UL1TR002384