Prospective Urban Rural Epidemiology Study

Обзор

To examine the impact of health determinants at the individual (e.g. health related behaviors) and societal level (e.g. environmental factors, health related policy, quality of health systems) on health outcomes (e.g. death, non-communicable disease development) across a range of socioeconomic and health resource settings. Additional components of this study will examine genetic factors for non-communicable diseases. This will be examined both through a cross sectional component, and prospectively (cohort component).

Подробное описание

1. To examine the relationship between societal influences and prevalence of risk factors and chronic noncommunicable diseases. Societal determinants are measured by an index of measures from each of the 4 domains of interest: built environment, food and nutrition policy, psychosocial/socioeconomic factors, and tobacco. 2. To examine the relationship between societal determinants and incidence of chronic noncommunicable disease events (e.g. cardiovascular disease, cancer) and on changes in rates of selected risk factors (e.g. smoking) 3. To examine the relationship between health related behaviors (e.g. diet, physical activity, smoking, alcohol) and health outcomes (e.g. death, non-communicable diseases) 4. The quality of health systems across a diverse range of health resource settings, and how this impacts health outcomes 5. Genetic factors for non-communicable diseases

Первичные конечные точки

• incident cardiovascular disease [Срок оценки: mean follow up of 10 years]

Вторичные конечные точки (12)

• incident cancer [Срок оценки: mean follow up of 10 years]
• Incident COPD [Срок оценки: mean follow up of 10 years]
• Incident Asthma [Срок оценки: mean follow up of 10 years]
• Pneumonia [Срок оценки: mean follow up of 10 years]
• Respiratory outcomes [Срок оценки: mean follow up of 10 years]
• All Cause Hospitalizations [Срок оценки: mean follow up of 10 years]
• Kidney disease [Срок оценки: mean follow up of 10 years]
• All cause and cause specific mortality [Срок оценки: mean follow up of 10 years]
• incident diabetes [Срок оценки: mean follow up of 10 years]
• obesity [Срок оценки: mean follow up of 10 years]
• hypertension [Срок оценки: mean follow up of 10 years]
• incident injuries [Срок оценки: mean follow up of 10 years]

Критерии участия

Критерии включения

• consenting adults between 35-70 years of age

Критерии исключения

• none

Критерии приведены из реестра в оригинале (на английском). Окончательную оценку соответствия проводит исследовательский центр.

Дизайн исследования

Модель наблюдения

Когортное

Центры проведения

Индия · 5 центров

• St John's Research Institute — Bangalore
• Health Action by People — Thiruvananthapuram
• Eternal Heart Care Centre and Research Institute — Jaipur
• Madras Diabetes Research Foundation — Chennai
• Post Graduate Institute of Medical Education and Research (PGIMER) — Chandigarh

Канада · 4 центра

• Simon Fraser University — Vancouver
• Population Health Research Institute — Hamilton
• University of Ottawa — Ottawa
• Université Laval Institut universitaire de cardiologie et de pneumologie de Québec — Québec

Малайзия · 2 центра

• Universiti Teknologi MARA, UCSI Universiti — Kuala Lumpur
• University Kebangsaan Malaysia — Kuala Lumpur

ЮАР · 2 центра

• School of Public Health, University of the Western Cape — Bellville
• North-West University — Potchefstroom

Аргентина · 1 центр

• Estudios Clinicos Latinoamerica ECLA — Rosario

Bangladesh · 1 центр

• Independent University, Bangladesh — Dhaka

Бразилия · 1 центр

• Dante Pazzanese Institute of Cardiology — São Paulo

Чили · 1 центр

• Universidad de La Frontera — Temuco

Китай · 1 центр

• State Key Laboratory of Cardiovascular Disease, Fuwai Hospital — Пекин

Колумбия · 1 центр

• Fundacion Oftalmologica de Santander - FOSCAL — Floridablanca

Иран · 1 центр

• Isfahan University of Medical Sciences — Isfahan

Казахстан · 1 центр

• Research Institute of Cardiology & Internal Diseases — Almaty

Kyrgyzstan · 1 центр

• Kyrgyz Society of Cardiology, National Center of Cardiology and Internal Disease — Bishkek

Пакистан · 1 центр

• Aga Khan University — Karachi

Palestinian Territories · 1 центр

• Birzeit University, Birzeit — Ramallah

Перу · 1 центр

• Universidad Peruana Cayetano Heredia — Lima

Филиппины · 1 центр

• University of Philippines, Section of Adult Medicine & Medical Research Unit — Manila

Польша · 1 центр

• Wroclaw Medical University & Department of Internal Medicine — Wroclaw

Россия · 1 центр

• Research Institute for Complex Issues of Cardiovascular Diseases — Kemerovo

Саудовская Аравия · 1 центр

• King Saud University — Riyadh

Швеция · 1 центр

• Sahlgrenska University Hospital/Östra Hospital — Gothenburg

Tanzania · 1 центр

• Pamoja Tunaweza Women Center — Moshi

Turkey (Türkiye) · 1 центр

• Istanbul Medeniyet University — Istanbul

ОАЭ · 1 центр

• Dubai Medical University — Dubai

Zimbabwe · 1 центр

• University of Zimbabwe College of Health Sciences — Harare

Публикации

• Dehghan M, Al Hamad N, Yusufali A, Nusrath F, Yusuf S, Merchant AT. Development of a semi-quantitative food frequency questionnaire for use in United Arab Emirates and Kuwait based on local foods. Nutr J. 2005 May 27;4:18. doi: 10.1186/1475-2891-4-18. PMID 15921524
• Merchant AT, Dehghan M, Chifamba J, Terera G, Yusuf S. Nutrient estimation from an FFQ developed for a Black Zimbabwean population. Nutr J. 2005 Dec 13;4:37. doi: 10.1186/1475-2891-4-37. PMID 16351722
• Merchant AT, Dehghan M. Food composition database development for between country comparisons. Nutr J. 2006 Jan 19;5:2. doi: 10.1186/1475-2891-5-2. PMID 16423289
• Vaz M, Bharathi AV, Thomas T, Yusuf S, Kurpad AV. The repeatability of self reported physical activity patterns in rural South India. Asia Pac J Clin Nutr. 2009;18(1):71-5. PMID 19329398
• Dehghan M, del Cerro S, Zhang X, Cuneo JM, Linetzky B, Diaz R, Merchant AT. Validation of a semi-quantitative Food Frequency Questionnaire for Argentinean adults. PLoS One. 2012;7(5):e37958. doi: 10.1371/journal.pone.0037958. Epub 2012 May 25. PMID 22662256
• Dehghan M, Martinez S, Zhang X, Seron P, Lanas F, Islam S, Merchant AT. Relative validity of an FFQ to estimate daily food and nutrient intakes for Chilean adults. Public Health Nutr. 2013 Oct;16(10):1782-8. doi: 10.1017/S1368980012004107. Epub 2012 Sep 21. PMID 22995762
• Dehghan M, Lopez Jaramillo P, Duenas R, Anaya LL, Garcia RG, Zhang X, Islam S, Merchant AT. Development and validation of a quantitative food frequency questionnaire among rural- and urban-dwelling adults in Colombia. J Nutr Educ Behav. 2012 Nov-Dec;44(6):609-13. doi: 10.1016/j.jneb.2010.10.001. Epub 2011 Jul 7. PMID 21737352
• Khatib R, Schwalm JD, Yusuf S, Haynes RB, McKee M, Khan M, Nieuwlaat R. Patient and healthcare provider barriers to hypertension awareness, treatment and follow up: a systematic review and meta-analysis of qualitative and quantitative studies. PLoS One. 2014 Jan 15;9(1):e84238. doi: 10.1371/journal.pone.0084238. eCollection 2014. PMID 24454721

Идентификаторы

NCT: NCT03225586 · PURE

Первоисточники (государственные реестры)

• ClinicalTrials.gov (NIH, США)

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