Aesthetic Masking and Resin Infiltration Time in MIH-affected Incisors
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: macroabrasion followed by oxidative pretreatment, macroabrasion alone.
- Who it may be relevant to
- Registry conditions: Molar Incisor Hypomineralization. Basic parameters: 8 years — 13 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Effectiveness of Transillumination-Guided Surface Pretreatment on Aesthetic Masking and Resin Infiltration Time in MIH-affected Incisors (A Randomised Clinical Trial)
Overview
Background: Resin infiltration often shows unpredictable outcomes in teeth affected by molar incisor hypomineralisation (MIH) due to variable enamel porosities, hypermineralised surface layers, and elevated protein content. Different pretreatment modalities alongside modified resin infiltration protocols have been suggested to enhance aesthetic masking and the required resin infiltration time. Aim: To compare the effectiveness of transillumination-guided 5.25% NaOCl pretreatment following macroabrasion, with macroabrasion alone, each with 10-second hydrochloric acid (HCl) etching intervals, on aesthetic masking and resin infiltration time required in MIH-affected incisors.
Interventions
- Other macroabrasion followed by oxidative pretreatment
Fine-grit aluminum oxide finishing stone under water coolant, using a high-speed handpiece to remove the superficial enamel layer, then 5.25% sodium hypochlorite will be applied to the labial lesion surface and agitated with a microbrush for one minute, then rinsed for 20 seconds. - Other macroabrasion alone
Fine-grit aluminum oxide finishing stone under water coolant, using a high-speed handpiece to remove the superficial enamel layer,
Primary outcome measures
- change in aesthetic masking effectiveness [Time frame: up to 6 months]
Secondary outcome measures (3)
- change in color stability [Time frame: up to 6 months]
- Changes in the patient-reported SCASS scores [Time frame: up to 6 months]
- change in patient satisfaction [Time frame: up to 6 months]
Eligibility criteria
Inclusion criteria
- Healthy children with MIH-related mild white creamy opacities on permanent incisors, code 1 according to the European Academy of Paediatric Dentistry (EAPD) criteria.
- Clinically detectable isolated lesions (whether homogeneous or heterogeneous on the incisal and middle thirds of the buccal surface of the selected teeth.
- Patients with score 3 (positive) or score 4 (definitely positive) according to Frankl behavioral rating scale
- Parents or legal guardians accepting to sign a written consent and join the study
Exclusion criteria
- MIH-affected permanent incisors with post-eruptive enamel breakdown, cavitated lesions, restorations, or previously treated with surface layer removal or remineralising agents in the previous six months.
- Children with an allergy history
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Outpatient Clinic of Pediatric dentistry, Faculty of dentistry, Alexandria University, Egy — Alexandria
Identifiers
NCT: NCT07753070 · 1338-05/2026