Opioid-Free Analgesia for Laparoscopic Cholecystectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: EOI with OFA, OFA.
- Who it may be relevant to
- Registry conditions: Analgesia After Laparoscopic Cholecystectomy. Basic parameters: 18 years — 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Center list to be confirmed — check the primary protocol.
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Analgesic Efficacy of Opioid-Free Anesthesia Protocol Combined With Ultrasound-Guided External Oblique Intercostal Plane Block for Laparoscopic Cholecystectomy: A Prospective Randomized Comparative Study
Overview
laparoscopic cholecystectomy (LC) is often accompanied by moderate-to-severe postoperative pain. opioid-free anesthesia (OFA) consists of a variety of non-opioid narcotic drugs and techniques.
Detailed description
opioid-free anesthesia (OFA) can control postoperative pain effectively and reduce opioid drug consumption.
The external oblique intercostal plane (EOI) block is easy to perform and may provide effective analgesia for laparoscopic cholecystectomy.
Interventions
- Procedure EOI with OFA
Patients will receive ultrasound-guided external oblique intercostal plane (EOI) block added to an opioid-free anesthesia (OFA) protocol - Drug OFA
Patients will receive an opioid-free anesthesia (OFA) protocol
Primary outcome measures
- the amount of fentanyl consumption used for pain relief in the first six hours after laparoscopic cholecystectomy (LC) under general anesthesia [Time frame: The first six hours after surgery]
Eligibility criteria
Inclusion criteria
- Adult patients scheduled for elective laparoscopic cholecystectomy (LC) surgery under general anesthesia, American Society of Anesthesiologists (ASA) physical status I-II, aged from 18 to 65 years old of either sex
Exclusion criteria
- Contraindications to regional block (coagulopathy, infection at the needle insertion site, or known allergy to amide local anesthetics)
- Pregnancy or breastfeeding women
- Body mass index (BMI) > 35 Kg/m2
- History of hepatic, renal, or cardiac disease
- Chronic opioid use, or history of chronic pain (pain present for more than 6 months)
- Thoracic deformity
- Neuropsychiatric disorders
- Patient refusal.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Center list to be confirmed — check the primary protocol.
Identifiers
NCT: NCT07750769 · SM82026