Impact of Non-surgical Periodontal Treatment on Targeted Metabolomics
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Probing depth reduction.
- Who it may be relevant to
- Registry conditions: Periodontitis. Basic parameters: 18 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on Targeted Metabolomics in Gingival Crevicular Fluid
Overview
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on targeted metabolomics in gingival crevicular fluid
Detailed description
A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis.
All the 60 patients with periodontitis are assessed for clinical, periodontal, and gingival crevicular fluid following of minimally invasive approach MINST or Q-SI (quadrantwise).
Measurements are taken before and after initial periodontal treatment in the periodontal subjects.
Interventions
- Other Probing depth reduction
Probing depth reduction in millimetres before and after treatment
Primary outcome measures
- Probing pocket depth [Time frame: 6 months]
Eligibility criteria
Inclusion criteria
- Diagnosis of Periodontitis
Exclusion criteria
- Periodontal treatment during the last 6 months
- Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months
- Pregnancy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Italy · 1 center
- AOU Policlinico G. Rodolico — Catania
Identifiers
NCT: NCT07740447 · 101-26