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Recruiting NCT07722260

Effect of Implementing Cough Augmentation Techniques on Weaning Outcomes Among Critically Ill Patients

No phase Interventional Physiological Parameters

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: cough augmentation techniques.
Who it may be relevant to
Registry conditions: Physiological Parameters. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

The study aims to determine the effect of implementing cough augmentation techniques on weaning outcomes among critically ill patients

Detailed description

Cough augmentation techniques are important interventions for critically ill patients who have impaired cough strength due to mechanical ventilation, neuromuscular weakness, sedation, or respiratory muscle dysfunction. These techniques, which include manual assisted cough, lung volume recruitment, and mechanical insufflation-exsufflation, enhance expiratory airflow and improve the clearance of airway secretions

Interventions

  • Other cough augmentation techniques
    the lung volume recruitment maneuver via MV was applied with assistant of the attended physician as follows: Use pressure-controlled ventilation and increase end-inspiratory volume (30 or 40 cm H2O for 30 to 40 seconds unless contraindicated) or inspiratory hold for 30 to 40 seconds to promote cough effectiveness. The patient serially inhales a volume of gas without exhalation until maximum insufflation capacity via the ventilator to facilitate breath-holding (if not contraindicated).

Primary outcome measures

  • weaning success [Time frame: within 7 days]

Eligibility criteria

Inclusion criteria

  • adult intubated patients
  • both sex

Exclusion criteria

  • patient with facial trauma
  • patient with tracheostomy tube

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Single blind
Primary purpose
Supportive care

Study locations

Egypt · 1 center
  • Faculty of Nursing, Damanhur University — Damanhūr

Publications

  • Chatwin M, Wakeman RH. Mechanical Insufflation-Exsufflation: Considerations for Improving Clinical Practice. J Clin Med. 2023 Mar 31;12(7):2626. doi: 10.3390/jcm12072626. PMID 37048708

Identifiers

NCT: NCT07722260 · 55-d

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗