Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Magnetic Resonance Cholangiopancreatography.
- Who it may be relevant to
- Registry conditions: Chronic Liver Disease and Cirrhosis, Liver Transplant; Complications, Donor Hepatectomy. Basic parameters: 18 years — 55 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- India
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Magnetic Resonance Cholangiopancreatography in Living Liver Donors and Its Relationship With Post Operative Recipient Biliary Complications - Open Label Randomised Controlled Trial
Overview
Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential
Detailed description
Living donor liver transplantation is widely accepted as an life-saving treatment for patients with end-stage liver diseases. Careful donor selection is essential to maximize the success and minimize the risk of postoperative complications in donors and recipients. Mapping of biliary anatomy is one of the critical assessments for donor selection and surgical planning ,Biliary reconstruction is considered as the "Achilles heel" of liver transplantation and adequate imaging assessment of biliary anatomy can largely benefit the biliary anastomosis. Preoperative imaging assessment of biliary anatomy is good for the selection of donors but may not indispensable for surgical planning and Intraoperative confirmative assessment of biliary anatomy with IOC was essential
Interventions
- Diagnostic test Magnetic Resonance Cholangiopancreatography
Magnetic Resonance Cholangiopancreatography is being excluded from list of Investigation as part of Non inferiority trial
Primary outcome measures
- To identify factors causing early biliary complications like type and number of arterial & biliary reconstruction, type of graft, number & size of Bile ducts in donor in both groups [Time frame: 6 month of postop]
Secondary outcome measures (2)
- Donor biliary complications in both group [Time frame: 1 month of postoperative period]
- Identify Risk factors for early Biliary complications in recipients [Time frame: till 6 months of Post operative period of Liver transplant]
Eligibility criteria
Inclusion criteria
- All prospective voluntary healthy liver donor of age 18-55
Exclusion criteria
- Type C/D Portal vein anatomy
- Left sided Gallbladder
- Right Posterior Graft
- Recipients undergoing Hepaticojejunostomy
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Diagnostic
Study locations
India · 1 center
- ILBS — New Delhi
Identifiers
NCT: NCT07715500 · IEC/2025/119/MA04