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Not yet recruiting NCT07715240

The HANAROSTENT® Multi-Hole™ Biliary Stent is Indicated for Use in the Palliative Treatment of Biliary Strictures Produced by Malignant Neoplasms and the Study is to Demonstrate Clinical Safety and Performance of the Multi-Hole™ Stent for the Palliative Treatment of Malignant Biliary Obstruction.

No phase Interventional Biliary Strictures Caused by Malignant Neoplasms

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Biliary Stent for the Palliative Treatment of Malignant Biliary Obstruction.
Who it may be relevant to
Registry conditions: Biliary Strictures Caused by Malignant Neoplasms. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Evaluation of the Clinical Safety and Performance of an Investigational Multi-Hole™ Biliary Stent for the Palliative Treatment of Malignant Biliary Obstruction

Overview

The objective of this study is to demonstrate clinical safety and performance of the HANAROSTENT® Multi-Hole™ Biliary Stent for the palliative treatment of malignant biliary obstruction.

Detailed description

The HANAROSTENT® Multi-Hole™ Biliary Stent is indicated for use in the palliative treatment of biliary strictures produced by malignant neoplasms.

Interventions

  • Device Biliary Stent for the Palliative Treatment of Malignant Biliary Obstruction
    Multi-hole anti-migration stent for biliary strictures produced by malignant neoplasms

Primary outcome measures

  • Primary Endpoints [Time frame: 6 Month]

Eligibility criteria

Inclusion criteria

  • Suspected or confirmed malignant non-hilar extrahepatic biliary obstruction including any of the following measures of biliary obstruction or patients undergoing neoadjuvant cancer treatment (chemotherapy and/or radiation) for malignant biliary obstruction

Clinical symptoms including (e.g., cholangitis, jaundice, pruritus, pale stools, and/or dark urine)

Biochemical evidence (Tbili > 3mg/dL)

High quality imaging (e.g., ultrasound, CT, MRCP, or ERCP)

≥ 18 years of age

Willing and able to provide informed consent

Exclusion criteria

  • Participation in another investigational study within 90 days prior to consent

Intrahepatic metastases that extensively involve both lobes of the liver

Patients with a distal malignant biliary obstruction due to potential resectable disease

Strictures that could not be traversed by the delivery system

Perforation of any duct within the biliary tree

Presence of a biliary self-expanding metal stent (SEMS), esophageal stent, or duodenal stent

Active viral hepatitis

Life expectancy of < 3 months

Patient has undergone (within 30 days prior to enrollment) or is planning to undergo brachytherapy with transpapillary or percutaneous implantation of intracavitary radiation sources

Unwilling or unable to comply with the follow-up schedule

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Single blind
Primary purpose
Supportive care

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07715240 · 2025-GI-01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗