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Recruiting NCT07714057

Effect of Hydrogen-rich Water During Tapering on Recovery After Functional Overreaching in Basketball Players

No phase Interventional Healthy Active Athletes

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Hydrogen-rich water, Placebo water.
Who it may be relevant to
Registry conditions: Healthy Active Athletes. Basic parameters: 18 years — 35 years · Male.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Czechia
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Effect of Hydrogen-rich Water Supplementation During Tapering on Recovery After Functional Overreaching in Competitive Male Basketball Players: A Randomized, Double-blind, Placebo-controlled Paralel-group Trial

Overview

The goal of this clinical trial is to evaluate whether hydrogen-rich water supplementation during tapering improves recovery after functional overreaching in competitive male basketball players aged 18-35 years. The main questions it aims to answer are: * Does hydrogen-rich water improve autonomic recovery after functional overreaching? * Does hydrogen-rich water improve recovery in biochemical, performance, and subjective feeling outcomes during tapering? Researchers will compare hydrogen-rich water to placebo (water containing no molecular hydrogen) to determine whether molecular hydrogen improves recovery after accumulated fatigue has been induced by functional overreaching. Participants will: * Complete a training cycle including normal training, functional overreaching, and tapering. * Consume hydrogen-rich or placebo water daily during the one-week tapering period. * Undergo repeated testing of autonomic nervous system, blood biochemical markers, performance, and subjective soreness.

Detailed description

The study consists of an initial screening and entry testing phase, followed by one week of normal training, two weeks of functional overreaching, and one week of tapering. During the functional overreaching period, training load is increased to approximately 120-130% of normal training load to induce accumulated fatigue. During the tapering period, training volume is reduced to approximately 50-60% of normal training volume to support recovery and performance rebound.

The molecular hydrogen is administered only during the tapering period. Participants in the experimental group consume 2.5 L per day of hydrogen-rich water. The total daily dose is divided into 0.5 L in the morning, 1.5 L around training, and 0.5 L in the evening. Participants in the placebo group consume visually matched placebo water according to the same total daily intake and timing schedule. Supplementation adherence is monitored using logs, dose counts, and attendance records. Participants are randomly assigned in a 1:1 ratio to either the experimental group or the placebo group. Randomization is performed using a block scheme and a computer random number generator.

Testing is performed at multiple time points: entry laboratory testing, baseline after normal training, post-functional overreaching, and post-taper. The primary interval for evaluation is the change from post-functional overreaching to post-taper. Statistical analysis is based on a t-test or analysis of variance. Data that not follow a normal distribution are treated using a logarithmic transformation or analyzed using nonparametric tests. The significance level is set at 0.05.

Interventions

  • Dietary supplement Hydrogen-rich water
    Hydrogen-rich water with molecular hydrogen concentration \>1.0 ppm.
  • Dietary supplement Placebo water
    Tap water without molecular hydrogen.

Primary outcome measures

  • RMSSD [Time frame: One-week change between post-overreaching and post-taper.]
Secondary outcome measures (12)
  • Creatine kinase [Time frame: One-week change between post-overreaching and post-taper.]
  • High-sensitivity C-reactive protein [Time frame: One-week change between post-overreaching and post-taper.]
  • Cortisol [Time frame: One-week change between post-overreaching and post-taper.]
  • Testosterone [Time frame: One-week change between post-overreaching and post-taper.]
  • Urea [Time frame: One-week change between post-overreaching and post-taper.]
  • Leukocytes [Time frame: One-week change between post-overreaching and post-taper.]
  • Lymphocytes [Time frame: One-week change between post-overreaching and post-taper.]
  • Neutrophils [Time frame: One-week change between post-overreaching and post-taper.]
  • Reactive strength index [Time frame: One-week change between post-overreaching and post-taper.]
  • Hangrip test [Time frame: One-week change between post-overreaching and post-taper.]
  • 20-m sprint [Time frame: One-week change between post-overreaching and post-taper.]
  • Repeated sprint [Time frame: One-week change between post-overreaching and post-taper.]

Eligibility criteria

Inclusion criteria

  • Competitive male basketball players.
  • Signed informed consent.
  • Completion of entry medical and laboratory screening.

Exclusion criteria

  • Acute injury or infection.
  • History or presence of relevant cardiovascular, respiratory, metabolic, or other disease that may affect the study results.
  • Use of medication affecting recovery markers or study results.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Basic science

Study locations

Czechia · 1 center
  • Palacky University, Faculty of Physical Culture — Olomouc

Identifiers

NCT: NCT07714057 · FTK_2026_13

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗