Analgesia Methods and Early Mobilization in Geriatric ICU Patients After Major Surgery
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Systemic Opioid Analgesia (± Multimodal), Epidural Analgesia, Peripheral Nerve Block (± Multimodal).
- Who it may be relevant to
- Registry conditions: Postoperative Pain, Delirium - Postoperative, Frailty, Postoperative Care in Geriatric Intensive Care Patients. Basic parameters: from 65 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Turkey (Türkiye)
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Effect of Analgesia Methods on Early Mobilization and Patient Satisfaction in Geriatric Patients Admitted to Intensive Care After Major Surgery
Overview
This study looks at how different pain-control methods affect how quickly older adults get out of bed and start moving again after major surgery. Researchers will observe patients aged 65 and older who are admitted to the intensive care unit (ICU) after major surgery. Doctors will use their usual pain-control methods - either medication given through a vein, an epidural, or a nerve block - based on standard clinical practice; the study team will not change or choose the treatment. The study will record how long it takes for each patient to first sit up, stand, or walk after surgery, along with pain levels, confusion (delirium), how satisfied patients are with their pain control, and how long they stay in the ICU. The goal is to better understand which pain-control approaches may help older patients recover and move more quickly and safely after major surgery.
Detailed description
Early mobilization is a key component of enhanced postoperative recovery in older adults and has been associated with reduced functional decline, shorter intensive care unit (ICU) and hospital stays, and fewer postoperative complications. However, postoperative pain remains one of the main barriers to early mobilization. Although several analgesic strategies are routinely used after major surgery, their comparative effects on functional recovery in critically ill geriatric patients have not been well established in real-world clinical practice.
This is a prospective, single-center observational cohort study designed to evaluate the association between routinely administered postoperative analgesic techniques and early postoperative recovery in geriatric surgical patients requiring ICU admission. Because the study is observational, all perioperative and postoperative management, including the choice of analgesic technique, will be determined exclusively by the treating clinicians according to institutional practice. No treatment allocation, randomization, or protocol-driven intervention will be performed.
Clinical and perioperative data will be collected prospectively from routine medical records, anesthesia documentation, ICU electronic records, and nursing charts using standardized case report forms. Data quality will be ensured through predefined data collection procedures and verification before database entry. The study does not require any additional diagnostic tests, invasive procedures, blood sampling, or alterations to routine patient care.
The findings are expected to provide real-world evidence regarding the relationship between commonly used postoperative analgesic strategies and recovery after major surgery in older adults. These results may help optimize perioperative pain management protocols and support future comparative and interventional studies aimed at improving functional recovery in the geriatric surgical population.
Interventions
- Drug Systemic Opioid Analgesia (± Multimodal)
Standard-of-care intravenous opioid-based analgesia, with or without additional non-opioid multimodal agents, administered per routine clinical practice. - Procedure Epidural Analgesia
Standard-of-care epidural analgesia administered per routine clinical practice. - Procedure Peripheral Nerve Block (± Multimodal)
Standard-of-care peripheral nerve block analgesia, with or without additional non-opioid multimodal agents, administered per routine clinical practice.
Primary outcome measures
- Time to First Mobilization [Time frame: From ICU admission until first achievement of ICU Mobility Scale level ≥1, assessed for up to 30 days.]
Secondary outcome measures (6)
- Postoperative Pain Score [Time frame: At ICU admission, and at 6, 12, 24, and 48 hours after ICU admission]
- Incidence of Delirium [Time frame: Assessed at least once daily for the first 3 days of ICU stay]
- Length of ICU Stay [Time frame: From ICU admission to ICU discharge, up to approximately 30 days]
- Total Opioid Consumption [Time frame: From ICU admission to ICU discharge, up to approximately 30 days]
- Patient Satisfaction with Analgesia [Time frame: Assessed once, prior to ICU discharge]
- Incidence and Type of Postoperative Complications [Time frame: From ICU admission to ICU discharge, up to approximately 30 days]
Eligibility criteria
Inclusion criteria
- Age 65 years or older
- ASA physical status classification I-IV
- Admitted to the intensive care unit (ICU) following major surgery
- ICU stay of at least 24 hours
Exclusion criteria
- Previously diagnosed advanced-stage dementia
- Inability to assess consciousness due to severe neurological deficit
- ICU stay of less than 24 hours
- Incomplete or insufficient clinical data
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Turkey (Türkiye) · 1 center
- University of Health Sciences, Prof. Dr. Cemil Taşçıoğlu City Hospital — Istanbul
Identifiers
NCT: NCT07709975 · CT-ERHO-AR-BA-04 · E-48670771-514.99-316163880