Evolution of Chronic Inflammatory Skin Diseases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: advanced sistemic therapies.
- Who it may be relevant to
- Registry conditions: Inflammatory Skin Disease. Basic parameters: from 12 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Italy
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
monocentric retrospective-prospective observational study evaluating the clinical evolution of common chronic inflammatory skin diseases, including atopic dermatitis, psoriasis, prurigo nodularis, chronic hand eczema, and hidradenitis suppurativa. The study will collect demographic, clinical, therapeutic, and validated clinimetric data from patients aged ≥12 years. Its primary aim is to describe changes in disease severity over time. Secondary objectives include identifying demographic, clinical, and treatment-related predictors of moderate-to-severe disease and unfavorable outcomes. Data will cover a 7-year retrospective period and a 10-year prospective follow-up.
Interventions
- Drug advanced sistemic therapies
evaluate the safety and efficacy of advanced sistemic therapies used in inflammatory skin diseases.
Primary outcome measures
- To describe changes over time in the clinical characteristics of the most common chronic inflammatory skin diseases (AD, PSO, HS, CHE, and PN). [Time frame: 120 months]
- To identify potential predictors of an unfavorable or favourable disease course [Time frame: 120 months]
Eligibility criteria
Inclusion criteria
Age ≥12 years.
Patients with a confirmed clinical diagnosis of atopic dermatitis (AD), prurigo nodularis (PN), psoriasis (PSO), chronic hand eczema (CHE), or hidradenitis suppurativa (HS) attending the dermatology outpatient clinics of Fondazione Policlinico Universitario A. Gemelli IRCCS.
Availability of clinical data at baseline and at subsequent follow-up visits performed according to routine clinical practice.
Exclusion criteria
Age <12 years; absence of the minimum required data (treatment start date and at least one follow-up visit with a clinical score).
Refusal or inability to understand and sign the informed consent form.
\-
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Italy · 1 center
- Fondazione Policlinico Agostino Gemelli IRCCS — Rome
Identifiers
NCT: NCT07708896 · 27085