Comparison of Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses Versus Non-Medicated Bandage Contact Lenses on Postoperative Pain Control After Photorefractive Keratectomy
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses, Contact Bandage Lenses.
- Who it may be relevant to
- Registry conditions: Refraction Error, Photorefractive Keratectomy. Basic parameters: 21 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Pakistan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Photorefractive keratectomy (PRK) is a well-established surface ablation procedure for the correction of refractive errors. Despite excellent visual and refractive outcomes, postoperative pain remains a significant concern, particularly during the first few days following surgery. This pain is primarily related to corneal epithelial removal, exposure of subepithelial nerve endings, and the subsequent inflammatory response. Effective pain management is therefore essential to enhance patient comfort, improve compliance with postoperative care, and increase overall surgical satisfaction. Therefore we will compare postoperative pain levels in patients undergoing PRK using ketorolac tromethamine 0.5%-soaked bandage contact lenses versus non-medicated bandage contact lenses.
Interventions
- Device Ketorolac Tromethamine 0.5%-Soaked Bandage Contact Lenses
Soaking Bandage Contact Lenses in ketorolac prior to application may provide sustained drug release at the ocular surface, thereby enhancing postoperative pain control while reducing the need for repeated topical administration.Recent studies have suggested that ketorolac-soaked Bandage Contact Lenses may significantly reduce pain following Photorefractive Keratectomy without adversely affecting epithelial healing - Device Contact Bandage Lenses
Bandage contact lenses (BCLs) are routinely used after PRK to protect the corneal surface, reduce mechanical irritation from blinking, and promote epithelial healing
Primary outcome measures
- Postoperative Pain [Time frame: 72 hours]
Secondary outcome measures (1)
- Epithelial Healing [Time frame: 72 hours]
Eligibility criteria
Inclusion criteria
- Participants selected to undergo photorefractive keratectomy for correction of refractive error after complete workup.
- Participants willing to participate in the study after detailed explanation of the research purpose.
Exclusion criteria
- Known hypersensitivity to NSAIDs or ketorolac.
- Presence of any systemic diseases affecting wound healing.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Supportive care
Study locations
Pakistan · 1 center
- Madina Teaching Hospital Faisalabad — Faisalābad
Identifiers
NCT: NCT07705763 · 11