Menu
Recruiting NCT07705061

Hertel Exophthalmometry Values in Mexican Adults

Observational Exophthalmometry Normal Exophthalmometric Values

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Hertel Exophthalmometry.
Who it may be relevant to
Registry conditions: Exophthalmometry, Normal Exophthalmometric Values. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Mexico
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Hertel Exophthalmometry Values in Mexican Adults and Their Association With Demographic Factors and Systemic Diseases

Overview

Proptosis assessment using Hertel exophthalmometry is an essential part of the ophthalmic examination, but normal reference values vary among different populations. This observational study aims to establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic characteristics (such as age and sex) and systemic diseases. Healthy adult participants and adults with selected systemic conditions will undergo standardized Hertel exophthalmometry measurements. The findings are expected to provide population-specific reference values that may improve the clinical assessment of orbital diseases in the Mexican population.

Detailed description

Background: Hertel exophthalmometry is the most commonly used method for measuring globe protrusion in clinical practice. Normal exophthalmometric values vary according to ethnicity, sex, age, and craniofacial anatomy; therefore, population-specific reference values are necessary for accurate clinical interpretation. Currently, normative data for Mexican adults are limited.

Objective: To establish normative Hertel exophthalmometry values in Mexican adults and to evaluate their association with demographic characteristics and systemic diseases.

Methods: This is a prospective observational study. Adult participants attending the Ophthalmology Department will be consecutively recruited after providing written informed consent. Hertel exophthalmometry measurements will be obtained using a standardized technique by trained examiners. Demographic information, including age and sex, as well as relevant medical history and systemic diseases, will be recorded. The primary outcome is the distribution of Hertel exophthalmometry values in the study population. Secondary analyses will assess associations between exophthalmometric measurements and demographic or systemic variables.

Expected Significance: The study will provide normative Hertel exophthalmometry values for the Mexican adult population and identify factors associated with physiological variations in globe protrusion. These findings may improve the clinical evaluation of patients with suspected orbital disease and facilitate interpretation of Hertel exophthalmometry measurements in routine ophthalmic practice.

Interventions

  • Diagnostic test Hertel Exophthalmometry
    Standardized bilateral Hertel exophthalmometry performed using a Hertel exophthalmometer to measure globe protrusion.

Primary outcome measures

  • Hertel Exophthalmometry Value [Time frame: At baseline]

Eligibility criteria

Inclusion criteria

  • Adults aged 18 years or older.
  • Mexican participants or individuals who self-identify as Mexican.
  • Ability to understand the study procedures and provide written informed consent.
  • Ability to undergo bilateral Hertel exophthalmometry.
  • Participants with or without previously diagnosed systemic diseases.

Exclusion criteria

  • Active thyroid eye disease
  • History of orbital trauma or orbital fracture.
  • Previous orbital surgery, orbital decompression, or surgery that may alter globe position.
  • Presence or history of an orbital tumor, orbital inflammation, or orbital infection.
  • Craniofacial abnormalities or facial asymmetry that may interfere with Hertel exophthalmometry.
  • Ocular or eyelid conditions that prevent accurate positioning or measurement with the Hertel exophthalmometer.
  • Inability to cooperate with the examination or obtain a reliable exophthalmometry measurement.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Mexico · 1 center
  • ✔ Instituto de Oftalmología Fundación Conde de Valenciana IAP — Mexico City

Identifiers

NCT: NCT07705061 · HERTEL-MX-2026-01

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗