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Not yet recruiting NCT07702539

NASA Exercise Prebreathe Study

No phase Interventional Decompression Sickness

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Oxygen Prebreathe and Hypobaric Exposure.
Who it may be relevant to
Registry conditions: Decompression Sickness. Basic parameters: 30 years — 60 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Exercise Prebreathe Study in Healthy Adult Volunteers to Evaluate Risk of Decompression Sickness During Simulated Spacewalk Conditions

Overview

This study evaluates oxygen prebreathe protocols and exercise conditions to reduce risk of decompression sickness during simulated extravehicular activity. Healthy adult volunteers will undergo oxygen prebreathe followed by hypobaric chamber exposure with monitoring for symptoms and ultrasound detection of bubbles.

Interventions

  • Procedure Oxygen Prebreathe and Hypobaric Exposure
    Prebreathe 100% oxygen followed by simulated spacewalk conditions in hypobaric chamber with exercise protocols.

Primary outcome measures

  • Number of participants with Decompression Sickness [Time frame: Up to 6 months]

Eligibility criteria

Inclusion criteria

  • Non-smoking volunteers aged 30-60 years
  • Able to meet VO2 peak requirements (>35 ml/kg/min males, >30 ml/kg/min females)

Exclusion criteria

  • Pregnancy
  • Lung disease, heart disease, hypertension, or diabetes
  • Musculoskeletal pain conditions
  • Requirement for regular medications such as analgesics

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Prevention

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07702539 · Pro00120426 · 80NSSC26P0252

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗