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Not yet recruiting NCT07692659

Ultrasound-Guided Parasternal/Rectus Sheath Block vs Erector Spinae Plane Block for Pain Control in Cardiac Surgery

No phase Interventional Analgesia Perioperative Analgesia Regional Block Technique

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Parasternal/ Rectus sheath block, Erector spinae plane block.
Who it may be relevant to
Registry conditions: Analgesia, Perioperative Analgesia, Regional Block Technique. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Comparison of Ultrasound Guided Bilateral Parasternal Block With Bilateral Rectus Sheath Block Versus Ultrasound Guided Bilateral Erector Spinae Plane Block in Controlling Intra and Post-operative Pain After Cardiac Surgeries

Overview

The researchers are working to improve recovery after heart surgery by reducing reliance on opioids. Newer regional anesthesia techniques can provide strong pain relief with fewer risks, but the choice of method depends on each patient's condition, medications, and surgical plan

Detailed description

Optimal anesthesia in cardiac surgery requires careful management to avoid sympathetic stimulation, with analgesia being central to patient safety and recovery. Traditionally, high-dose opioids were used, but this approach delays extubation, conflicting with fast-track protocols that emphasize early extubation. Consequently, opioid-free analgesia has gained importance, employing regional techniques such as neuraxial, paravertebral, and fascial plane blocks.

Thoracic epidural analgesia (TEA) offers effective pain control and reduces perioperative cardiovascular and respiratory complications. However, its use in anticoagulated patients raises concern for epidural hematoma. Alternatives like paravertebral and fascial plane blocks provide comparable analgesia with lower risk. The erector spinae plane block (ESPB) reduces analgesic requirements, though deep blocks still pose bleeding risks.

Superficial plane blocks are therefore clinically valuable. The parasternal intercostal block-targeting anterior cutaneous branches of intercostal nerves-has emerged as a safe option for patients undergoing median sternotomy while on anticoagulant or antiplatelet therapy. Additionally, bilateral rectus sheath block can reduce chest tube insertion pain after cardiac surgery.

Interventions

  • Procedure Parasternal/ Rectus sheath block
    the parasternal block will be performed parasternally at the level of fifth rib to the plane between the pectoralis major and the internal intercostal muscle. The rectus sheath block will be performed through injection in the plane posterior to the rectus abdominis muscle and anterior to the posterior rectus sheath
  • Procedure Erector spinae plane block
    injection above the transverse process

Primary outcome measures

  • Numeric rating score [Time frame: 24 hours]
Secondary outcome measures (4)
  • postoperative opioid consumption [Time frame: 24 hours]
  • extubation time [Time frame: immediate postoperative]
  • first time to request analgesia [Time frame: 24 hours]
  • peri-operative hemodynamics [Time frame: intraoperative and 24 hours]

Eligibility criteria

Inclusion criteria

  • Both sexes,
  • ASA III-IV patients
  • body mass index between 20- 35 kg/m2
  • adult patients above 18 years old will be included in the study

Exclusion criteria

  • Patients with global hypokinesia
  • ejection fraction < 40%
  • low platelet count
  • coagulation impairment
  • deformity in the vertebral column
  • severe renal and hepatic impairment
  • any known allergy to the drugs used

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07692659 · ECC-2025-64

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗