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Not yet recruiting NCT07687082

Prevalence and Risk Factors for Chronic Post-Surgical Pain Following Video-Assisted Thoracic Surgery : The EVATHO Prospective Bicentric Cohort Study.

— Observational Chronic Post-surgical Pain Postoperative Pain After Thoracic Surgery Neuropathic Pain Thoracic Surgical Procedures

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Chronic Post-surgical Pain, Postoperative Pain After Thoracic Surgery, Neuropathic Pain, Thoracic Surgical Procedures. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Center list to be confirmed — check the primary protocol.
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Study of the Prevalence of Chronic Postoperative Pain After Video-Assisted Thoracic Surgery: A Bicentric Cohort Study

Overview

Chronic post-surgical pain (CPSP) remains a common complication after thoracic surgery and may significantly impair patients' quality of life. Although the widespread adoption of video-assisted thoracic surgery (VATS) has reduced surgical trauma and improved postoperative recovery, a substantial proportion of patients still develop persistent pain. The EVATHO study is a multicenter prospective observational cohort designed to determine the prevalence of CPSP three months after VATS and to identify perioperative factors associated with its development. Adult patients undergoing thoracic surgery by VATS at Montpellier and Nice University Hospitals will be prospectively enrolled. Pain intensity, neuropathic pain characteristics, anxiety, depression, quality of life, and analgesic consumption will be assessed using validated questionnaires during the perioperative period and at 1 and 3 months after surgery. The results of this study may help identify patients at increased risk of CPSP and improve perioperative pain management strategies following thoracic surgery.

Primary outcome measures

  • Number of participants with chronic post-surgical pain [Time frame: 3 months after surgery.]
Secondary outcome measures (9)
  • Postoperative pain at 1 month after VATS [Time frame: 1 month after thoracic surgery]
  • Visual Analogue Scale (VAS) pain score [Time frame: Preoperative assessment, postoperative day 1, postoperative day 2, 1 month, and 3 months after surgery.]
  • Cumulative postoperative opioid consumption. [Time frame: Postoperative day 1, postoperative day 2, 1 month, and 3 months after surgery.]
  • Douleur Neuropathie 4 (DN4) score [Time frame: Preoperative assessment, postoperative day 1, postoperative day 2, 1 month, and 3 months after surgery.]
  • Hospitalier Anxiety and depression Scale (HADS) anxiety score [Time frame: Preoperative assessment, 1 month, and 3 months after surgery.]
  • Hospital Anxiety and Depression Scale (HADS) depression score [Time frame: Preoperative assessment, 1 month, and 3 months after surgery]
  • Brief Pain Inventory (BPI) pain interference score [Time frame: 1 month and 3 months after surgery.]
  • Short Form-12 Physical component summary score [Time frame: Preoperative assessment, 1 month, and 3 months after surgery.]
  • Short form-12 Mental Component Summary score [Time frame: Preoperative assessment, 1 month and 3 months after surgery]

Eligibility criteria

Inclusion criteria

  • Adult patients undergoing video-assisted thoracic surgery (VATS) for thoracic surgery

Exclusion criteria

  • Age <18 years
  • Adults under legal protection or unable to provide informed non-opposition
  • Patients unable to understand or complete the study questionnaires
  • Patients not affiliated with a French health insurance scheme.
  • Adults under legal protection, including judicial safeguard, guardianship, or curatorship.
  • Participation in another clinical study involving an ongoing exclusion period.
  • Pregnant or breastfeeding women.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Center list to be confirmed — check the primary protocol.

Identifiers

NCT: NCT07687082 · RECHMPL 25_0555

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗