Recruiting NCT07677826
Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: surgical depigmentation, Coenzyme Q10, Vitamin C, Surgical Gingival Depigmentation Coenzyme Q10 Vitamin C.
- Who it may be relevant to
- Registry conditions: Depigmentation Treatment, Depigmentation. Basic parameters: 18 years — 45 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Egypt
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Ffect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation a Randomized Clinical Study
Overview
This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.
Interventions
- Procedure surgical depigmentation
Surgical gingival depigmentation performed using the conventional scalpel technique. The pigmented gingival epithelium is surgically removed under local anesthesia to eliminate melanin pigmentation and improve gingival esthetics. - Dietary supplement Coenzyme Q10
Coenzyme Q10 administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival depigmentation. - Dietary supplement Vitamin C
Vitamin C administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival depigmentation. - Dietary supplement Surgical Gingival Depigmentation Coenzyme Q10 Vitamin C
Coenzyme Q10 and vitamin c administered according to the study protocol following surgical gingival depigmentation to evaluate its effect on wound healing and gingival repigmentation.
Primary outcome measures
- Change in gingival pigmentation intensity using the Dummett Oral Pigmentation Index (DOPI). The DOPI scale from 0 to 3, where:0 = No clinical pigmentation ,1 = Mild pigmentation , 2 = Moderate pigmentation 3 = Heavy pigmentation [Time frame: 1 week, 1 month and 3 months. ,6 months]
Eligibility criteria
Inclusion criteria
- Systemically healthy patient of both genders aged from 18-45 years.
- Presence of bilateral physiologic gingival pigmentation in the anterior maxillary or mandibular region DOPI grades III-IV only.
- Good oral hygiene.
- Thick gingival phenotype.
Exclusion criteria
- Patient clinically diagnosed with periodontitis.
- Pregnant or lactating females.
- Patient with previous treatment of gingival hyperpigmentation.
- History of hypersensitivity to any study material.
- Patients who are active or previous smokers.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Double blind
- Primary purpose
- Treatment
Study locations
Egypt · 1 center
- Faculty of dental medicine for girls? ALAZHAR University, Cairo, egypt — Nāşir
Identifiers
NCT: NCT07677826 · P-ME-26-1